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HIV Patients Experience Better Kidney Transplant Outcomes than Hepatitis C Patients, According to Penn Study

HIV Patients Experience Better Kidney Transplant Outcomes than Hepatitis C Patients, According to Penn Study

HIV (human immunodeficiency virus)-positive kidney transplant patients experienced superior outcomes when compared to kidney transplant patients with Hepatitis C and those infected with both HIV and Hepatitis C, according to a study led by researchers at the Perelman School of Medicine at theUniversity of Pennsylvania and published online in Kidney International.

Anna Duerr

Odds of Reversing ICU Patients' Prior Preferences to Forgo Life-Sustaining Therapies Vary Widely Across the U.S., according to Penn Study

Odds of Reversing ICU Patients' Prior Preferences to Forgo Life-Sustaining Therapies Vary Widely Across the U.S., according to Penn Study

Intensive care units across the United States vary widely in how they manage the care of patients who have set preexisting limits on life-sustaining therapies, such as authorizing do-not-resuscitate (DNR) orders and prohibiting interventions such as feeding tubes or dialysis, according to new research from the Perelman School of Medicine at the University of Pennsylvania. Their work is published in the current issue of JAMA Internal Medicine.

Lee-Ann Donegan

Most NFL Players with Injuries to the Midfoot Return to Game Action, Penn Medicine Study Finds

Most NFL Players with Injuries to the Midfoot Return to Game Action, Penn Medicine Study Finds

Nearly 93 percent of National Football League (NFL) athletes who sustained traumatic injuries to the midfoot returned to competition less than 15 months after injury and with no statistically significant decrease in performance, according to new research from the Perelman School of Medicine at the University of Pennsylvania. The findings, which focus on Lisfranc injuries – characterized by fracture of the midfoot bones and/or disruption of the midfoot ligaments – between 2000-2010, were presented today at the American Association of Orthopaedic Surgeons (AAOS) annual conference in Las Vegas.

Katie Delach

Malnourished Patients are More Likely to Suffer Postoperative Complications than Morbidly Obese Patients Following Knee, Hip Replacement, Penn Study Finds

Malnourished Patients are More Likely to Suffer Postoperative Complications than Morbidly Obese Patients Following Knee, Hip Replacement, Penn Study Finds

Malnourished patients are more likely to have complications following total knee or hip replacement surgeries than morbidly obese patients,according to new research from researchers at the Perelman School of Medicine at the University of Pennsylvania. The findings are being presented at the American Academy of Orthopaedic Surgeons Annual Meeting in Las Vegas March 24-28. 

Katie Delach

Penn Medicine Study: In Debated Surgical Procedure, Technique Trumps Technology

Penn Medicine Study: In Debated Surgical Procedure, Technique Trumps Technology

A team of orthopedic surgeons from the Perelman School of Medicine at the University of Pennsylvania has found that modern technology for healing distal femur fractures is as safe and effective as its more established alternative, without a potential shortfall of the older approach.

Katie Delach

Roseroot Herb Shows Promise as Potential Depression Treatment Option, Penn Team Finds

Roseroot Herb Shows Promise as Potential Depression Treatment Option, Penn Team Finds

Rhodiola rosea (R. rosea), or roseroot, may be a beneficial treatment option for major depressive disorder (MDD), according to results of a study in the journal Phytomedicine led by Jun J. Mao, MD, MSCE, associate professor of Family Medicine, Community Health and Epidemiology and colleagues at the Perelman School of Medicine of University of Pennsylvania.

Greg Richter

Penn Medicine Experts Unveil Two New Ways to Identify Joint Replacement Patients at Risk for Post-Operative Complications

Penn Medicine Experts Unveil Two New Ways to Identify Joint Replacement Patients at Risk for Post-Operative Complications

Orthopedic surgeons from the Perelman School of Medicine at the University of Pennsylvania have developed two new prediction tools aimed at identifying total hip and knee replacement patients who are at-risk of developing serious complications after surgery. The first tool identifies patients who have risk factors that should disqualify them from undergoing same-day (outpatient) or short-stay (overnight) total hip and knee replacement procedures, opting instead for traditional recovery pathways in the hospital.

Katie Delach

New Penn Program Studies the Body’s Cells, One By One

New Penn Program Studies the Body’s Cells, One By One

By Sarah Welsh Cancer starts with a single cell going haywire. What is it about that one cell that makes it different from the rest, setting it on a path of destruction? A new program at the University of Pennsylvania may help find an answer to that and many other questions.

Katherine Unger Baillie

Penn Medicine: Genomewide Screen of Learning in Zebrafish Identifies Enzyme Important in Neural Circuit

Penn Medicine: Genomewide Screen of Learning in Zebrafish Identifies Enzyme Important in Neural Circuit

Researchers at the Perelman School of Medicine at the University of Pennsylvaniadescribe the first set of genes important in learning in a zebrafish model in the journal Neuron this week. “Using an in-depth analysis of one of these genes, we have already revealed an important relevant signaling pathway,” says senior author Michael Granato, PhD, a professor of Cell and Developmental Biology. “The proteins in this pathway could provide new insights into the development of novel pharmacological targets.”

Karen Kreeger