Perelman School of Medicine

Penn Medicine researchers, in a continuation of their groundbreaking work to better understand how anesthesia works in the body, have found the first new class of novel anesthetics since the 1970s. Their findings, published in February issue of Anesthesiology, detail the processes through which the group uncovered these compounds.

As the United States population has doubled since 1955, the number of inpatient psychiatric beds in the United States has been cut by nearly 95 percent to just 45,000, a wholly inadequate equation when considering that there are currently 10 million U.S. residents with serious mental illness.

When retrievable inferior vena cava (IVC) filters were approved for use in the United States in 2003 to prevent pulmonary embolism among patients unable to receive the standard blood thinner treatment, many experts anticipated most of them would be removed when no longer needed and IVC filter complications would decrease.

Here’s another potential reason to live up in the mountains. Lung cancer rates in both smokers and non-smokers are lower in higher-elevation counties in the western part of the United States, suggesting that oxygen may promote the incidence of lung cancer, according to a new study co-authored by a student at the Perelman School of Medicine at the University of Pennsylvania.

Nearly 70 percent of smokers who try to quit relapse within one week – daunting odds for people trying to kick the habit. Researchers have long theorized that some individuals may be genetically programmed to have an easier time than others, but with few clues about why, experts have been unable to guide smokers looking to quit toward a strategy – the nicotine patch versus prescription pills, for instance – with the best chance of success.

Transcatheter aortic valve replacement, or TAVR, has been called one of the biggest advances in cardiac surgery in recent years. The procedure delivers a new, collapsible aortic valve through a catheter to the valve site within the heart - a repair that otherwise requires open heart surgery. 

New Year’s weight loss resolutions are in full swing, but despite all the hype about the latest wearable tracking devices, there’s little evidence that this technology alone can change behavior and improve health for those that need it most, according to a new online-first viewpoint piece in JAMA.

“In today’s world, the stereotype of the nerdy scientist, by himself, looking at a microscope, is no longer accurate and no longer useful,” says Gabriel Innes, a third-year student in the University of Pennsylvania School of Veterinary Medicine.

Adding radiation treatment to hormone therapy saves more lives among older men with locally advanced prostate therapy than hormone therapy alone, according to a new study in the Journal of Clinical Oncology this week from Penn Medicine researchers.