Perelman School of Medicine

A first-of-its-kind set of questions included in the Internal Medicine In-Training Examination (IM-ITE) illustrates the need to better evaluate resident proficiency in high-value care (HVC), according to a new study published in Annals of Internal Medicine.

A new form of gene therapy for boys with X-linked severe combined immunodeficiency syndrome (SCID-X1), a life-threatening condition also known as “bubble boy” disease, appears to be both effective and safe, according to an international clinical trial with sites in Boston, Cincinnati, Los Angeles, London, and Paris. 

The University of Pennsylvania’s Basser Research Center for BRCA has announced $6.9 million to research teams both at Penn and at five other institutions across the United States, aimed at advancing the care of patients living with BRCA1 and BRCA2 mutations through multi-disciplinary collaboration.

By Madeleine Stone  @themadstone

A $10 million gift to the University of Pennsylvania to name the Paul F. Harron, Jr. Lung Center will pay tribute to the late broadcast and cable television pioneer and bolster Penn Medicine’s efforts in providing the most advanced diagnosis and treatment of chronic lung disorders, the University announced.

Online learning interventions and small group debriefings can improve medical residents’ attitudes and communication skills toward patients with substance use disorders, and may result in improved care for these patients, according to a new study from the Perelman School of Medicine at the University of Pennsyl

An automated early warning and response system for sepsis developed by Penn Medicine experts has resulted in a marked increase in sepsis identification and care, transfer to the ICU, and an indication of fewer deaths due to sepsis.

Nearly 60,000 Americans suffer from myasthenia gravis (MG), a non-inherited autoimmune form of muscle weakness. The disease has no cure, and the primary treatments are nonspecific immunosuppressants and inhibitors of the enzyme cholinesterase.

Obesity is a risk factor for many health problems, but a new Penn Medicine study published this month in the journal Sleep suggests having a larger tongue with increased levels of fat may be a sign of obstructive sleep apnea (OSA) in obese adults.

It’s an early lesson in genetics: we get half our DNA from Mom, half from Dad. But that straightforward explanation does not account for a process that sometimes occurs when cells divide. Called gene conversion, the copy of a gene from Mom can replace the one from Dad, or vice versa, making the two copies identical.