Perelman School of Medicine

The Penn Medicine Center for Health Care Innovation will fund three new initiatives in the second round of its  Innovation Grant Program. The program encourages Penn employees and students to submit their ideas for advancing health and health care delivery.

In the largest group of results to date, researchers from Penn Medicine’s Abramson Cancer Center and other institutions have shown in clinical trials that the malaria drug hydroxychloroquine (HCQ) blocked autophagy in a host of aggressive cancers—glioblastoma, melanoma, lymphoma and myeloma, renal and colon cancers—and in some cases helped stabilize disea

Nearly half of all adults in the United States suffer from the gum disease periodontitis, and 8.5 percent have a severe form that can raise the risk of heart disease, diabetes, arthritis and pregnancy complications.

Studies of vaccine programs in the developing world have revealed that individuals with chronic infections such as malaria and hepatitis tend to be less likely to develop the fullest possible immunity benefits from vaccines for unrelated illnesses.

While large genetic testing panels promise to uncover clues about patients’ DNA, a team of researchers from Penn Medicine’s Abramson Cancer Center (ACC) has found that those powerful tests tend to produce more questions than they answer.

Despite claims suggesting otherwise, inappropriate cancer patient demands are few and very rarely lead to unnecessary tests and treatments from their health care providers, according to new results from a study that will be presented by researchers in the Abramson Cancer Center  (ACC) and the Perelman Sch

Breastfeeding, tubal ligation – also known as having one’s “tubes tied” – and oral contraceptives may lower the risk of ovarian cancer for some women with BRCA gene mutations, according to a comprehensive analysis from a team at the University of Pennsylvania's Basser Research Center for BRCA and the 

A University of Pennsylvania researcher has discovered that the common selective serotonin reuptake inhibitor (SSRI) citalopram arrested the growth of amyloid beta, a peptide in the brain that clusters in plaques that are thought to trigger the development of Alzheimer’s disease (AD).

Ancient philosophers looked to alchemy for clues to life everlasting. Today, researchers look to their yeast. These single-celled microbes have long served as model systems for the puzzle that is the aging process, and in this week’s issue of Cell Metabolism, they fill in yet another piece.

A group of health care and policy experts from the Perelman School of Medicine at the University of Pennsylvania is urging health care institutions to look more to their own in-house personnel, including physicians and nurses, as a source of new ideas for improving how care is delivered.