Perelman School of Medicine

Over the last few decades researchers have characterized a set of clock genes that drive daily rhythms of physiology and behavior in all types of species, from flies to humans. Over 15 mammalian clock proteins have been identified, but researchers surmise there are more.

Despite decades of common use for surgeries of all kinds, the precise mechanism through which general anesthesia works on the body remains a mystery. This may come as a surprise to the millions of Americans who receive inhaled general anesthesia each year.

When we get sick it feels natural to try to hasten our recovery by getting some extra shuteye. Researchers from the Perelman School of Medicine at the University of Pennsylvania found that this response has a definite purpose, in fruitflies: enhancing immune system response and recovery to infection.

Nonsteroidal antinflamatory drugs (NSAIDs) that block an enzyme called COX-2 relieve pain and inflammation but can cause heart attacks, stroke, heart failure, and even sudden cardiac death. This has prompted a decade-plus search for safer, but still effective, alternatives to these commonly prescribed, pain-relieving drugs.

WHO            Tebelelo Secretse, ambassador of Botswana to the United States

Proton therapy is in the proverbial chicken or the egg scenario.  Companies are pulling back on reimbursements to treat some cancers—notably prostate, breast and lung—because of the added expense and limited evidence to back it up.

Three million Americans suffer from Hepatitis C Virus (HCV) infection, with baby boomers representing a large proportion of those infected.

When workers and organizations circumvent computer passwords and security rules, they unwittingly open the door to hackers, according to a study co-authored by Ross Koppel, an adjunct professor of sociology at the University of Pennsylvania.

Mom always said you need your sleep, and it turns out, she was right.

Playing an active role in their radiation treatment decisions leaves cancer patients feeling more satisfied with their care, and may even relieve psychological distress around the experience, researchers from the Perelman School of Medicine at the University of Pennsylvania report in the