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PHILADELPHIA — Understanding how any disease progresses is one of the first and most important steps towards finding treatments to stop it. This has been the case for such brain-degenerating conditions as Alzheimer's disease.
PHILADELPHIA — Fifty years ago, UK researcher John Gurdon demonstrated that genetic material from non-reproductive cells could be reprogrammed into an embryonic state when transferred into an egg.
PHILADELPHIA — The cancer-causing form of the gene Myc alters the metabolism of mitochondria, the cell’s powerhouse, making it dependent on the amino acid glutamine for survival. In fact, 40 percent of all “hard-to-treat” cancers have a mutation in the Myc gene.
PHILADELPHIA — Fat cells store excess energy and signal these levels to the brain.
PHILADELPHIA — As researchers work on reconfiguring cells to take on new regenerative properties, a new review from Penn Medicine plastic surgeons sheds additional light on the potential power of adipose-derived stem cells - or adult stem cells harvested from fatty tissue - in reconstructive and regenerative medicine.
LOS ANGELES — Lance Becker, MD, a professor of Emergency Medicine and director of the Center for Resuscitation Science at the Perelman School of Medicine at the University of Pennsylvania, will receive the American Heart Association’s 2012 Award for Lifetime Achieve
PHILADELPHIA — An international effort led by researchers at the Perelman School of Medicine at the University of Pennsylvania has resulted in positive phase 3 clinical trial results for a new medicine to treat patients suffering from a rare and deadly cholesterol disorder.
When Chyke Doubeni was in high school, he thought he might become an economist, like his older brother.
PHILADELPHIA — Most healthy cells rely on a complicated process to produce the fuel ATP. Knowing how ATP is produced by the cell’s energy storehouse – the mitochondria -- is important for understanding a cell’s normal state, as well as what happens when things go wrong, for example in cancer, cardiovascular disease, neurodegeneration, and many rare disorders of the mitochondria.
According to Aditi Vasan of the Leonard Davis Institute and Perelman School of Medicine, evidence is mounting in favor of the model of training community health workers to help their neighbors connect to government and health care services.
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According to Thomas Wadden of the Perelman School of Medicine, people taking GLP-1 drugs are finding that daily experiences that used to trigger a compulsion to eat or think about food no longer have that effect.
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PIK Professor Ezekiel Emanuel says that incessantly preparing for old age mistakes a long life for a worthwhile one.
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Shoshana Aronowitz of the School of Nursing and Ashish Thakrar of the Perelman School of Medicine comment on the lack of specificity in Philadelphia’s plan to remove drug users from Kensington and on the current state of drug treatment in the city.
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The Hospital of the University of Pennsylvania has been named one of the most recommended acute-care facilities by patients in the Philadelphia area.
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