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Perelman School of Medicine
Malfunctioning Gene Associated With Lou Gehrig’s Disease Leads to Nerve-Cell Death in Mice
PHILADELPHIA – Lou Gehrig’s disease, or amyotrophic lateral sclerosis (ALS), and frontotemporal lobar degeneration (FTLD) are characterized by protein clumps in brain and spinal-cord cells that include an RNA-binding protein called TDP-43. This protein is the major building block of the lesions formed by these clumps.
Penn Medicine Selected as Field Trial Site for DSM-5
PHILADELPHIA – Penn Medicine has been selected as one of seven adult field trial sites to test proposed diagnostic criteria for the American Psychiatric Association’s (APA) fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM).
Structure of Key Molecule in Immune System Provides Clues for Designing Drugs, According to Penn Study
PHILADELPHIA - A team from the University of Pennsylvania School of Medicine and Utrecht University has deciphered a key step in an evolutionarily old branch of the immune response. This system, called complement, comprises a network of proteins that “complement” the work of antibodies in destroying foreign invaders.
Penn Researchers Identify Potential Target for Breast Cancer Therapy
PHILADELPHIA – Overexpression or hyperactivation of ErbB cell-surface receptors drives the growth of many breast cancers. Drugs, like Herceptin, that block the receptors’ signals halt tumor progression in some patients. However, not all patients’ tumors respond, with some becoming resistant over time.
Penn Medicine Establishes Hand Transplant Program
PHILADELPHIA - The Penn Transplant Institute, the Department of Orthopaedic Surgery and the Division of Plastic Surgery at the Hospital of the University of Pennsylvania (HUP) have collaborated to form the Penn Hand Transplant Program.
Weightlifting Slashes Lymphedema Risk After Breast Cancer Treatment
(SAN ANTONIO) -- Weightlifting may play a key role in a program to prevent the painful limb-swelling condition lymphedema following breast cancer treatment, according to new research from the University of Pennsylvania School of Medicine.
Not Only Skin Deep: Penn Study on Skin Formation Suggests Strategies to Fight Skin Cancer
PHILADELPHIA - In a study published in the journal Developmental Cell, Sarah Millar PhD, professor of Dermatology and Cell & Developmental Biology at the University of Pennsylvania School of Medicine, and colleagues demonstrate that a
Personalized Vaccine for Lymphoma Patients Extends Disease-Free Survival by Nearly Two Years
(ORLANDO, Fla.) –A personalized vaccine is a powerful therapy to prevent recurrence among certain follicular lymphoma patients, according to the latest results of ongoing research led by the University of Pennsylvania School of Medicine.
Color-Changing “Blast Badge” Detects Exposure to Explosive Shock Waves
PHILADELPHIA - Mimicking the reflective iridescence of a butterfly's wing, investigators at the University of Pennsylvania School of Medicine and School of Engineering and Applied Sciences have developed a color-changing patch that could be worn on soldiers' helmets and uniforms t
First Blood Test to Determine Cognitive Impairment in Parkinson’s Disease Developed at Penn
PHILADELPHIA –Researchers at the University of Pennsylvania School of Medicine’s Udall Center for Parkinson's Research have developed the first blood-based biomarker test to predict cognitive decline in Parkinson’s disease (PD).
In the News
What’s going on with tranq?
Jeanmarie Perron of the Perelman School of Medicine says that the appearance and progression of skin ulcers and tissue loss on xylazine users is different than with other intravenous drugs.
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It’s time to end the Medicare-Medicaid merry-go-round
In an opinion essay, Rachel M. Werner of the Leonard Davis Institute, Wharton School, and Perelman School of Medicine says that Medicare and Medicaid fail to integrate coverage and coordinate care across their two plans.
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Inside Penn’s transfer center
Penn Medicine’s transfer command center gets patients from affiliated hospitals and hospitals outside Philadelphia to specialized care that can save lives, with comments from CEO Kevin Mahoney.
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Operating rooms are major sources of greenhouse gasses. Penn is eliminating a form of anesthesia that hangs in the air for more than a decade after use
Penn Medicine is phasing out the anesthesia desflurane at four of its six hospitals to eliminate harmful greenhouse gases, with remarks from Greg Evans.
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Broad Street runners from Penn are racing with gyroscopes to study the Achilles tendon
Casey Jo Humbyrd and Josh Baxter of the Perelman School of Medicine and colleagues will track data from running the Broad Street Run to understand how a healthy Achilles tendon functions.
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