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At the Crossroads of Chromosomes: Penn Study Reveals Structure of Cell Division’s Key Molecule

At the Crossroads of Chromosomes: Penn Study Reveals Structure of Cell Division’s Key Molecule

PHILADELPHIA – On average, one hundred billion cells in the human body divide over the course of a day. Most of the time the body gets it right but sometimes, problems in cell replication can lead to abnormalities in chromosomes resulting in many types of disorders, from cancer to Down Syndrome.

Successful Periodontal Therapy May Reduce the Risk of Preterm Birth, According to Penn Dental Study

Successful Periodontal Therapy May Reduce the Risk of Preterm Birth, According to Penn Dental Study

PHILADELPHIA –- A collaboration led by a periodontal researcher from the University of Pennsylvania School of Dental Medicine has found a possible link between the success of gum-disease treatment and the likelihood of giving birth prematurely, according to a study published in the journal BJOG: An Inter

Jacquie Posey

Using the Structure of the Epidermal Growth Factor Receptor to Fight Cancer

Using the Structure of the Epidermal Growth Factor Receptor to Fight Cancer

PHILADELPHIA - Many types of tumors grow because of over-expression or a mutation of a protein called the epidermal growth factor receptor (EGFR), normally regulated by a hormone-like peptide called the epidermal growth factor (EGF).

Karen Kreeger

Dr. J. Larry Jameson to Lead Penn Medicine

Dr. J. Larry Jameson to Lead Penn Medicine

PHILADELPHIA -- J. Larry Jameson, M.D., Ph.D., has been named the next executive vice president of the University of Pennsylvania for the Health System and dean of Penn’s School of Medicine, effective July 1, 2011.

Lori N. Doyle

Preventive Surgeries Linked to Lower Risk of Cancer for Women with BRCA1/2 Gene Mutations

Preventive Surgeries Linked to Lower Risk of Cancer for Women with BRCA1/2 Gene Mutations

Women who have inherited mutations in the BRCA1 or BRCA2 (BRCA1/2) genes have substantially elevated risks of developing breast and ovarian cancer.  A study that will appear in the September 1 issue of The Journal of the American Medical Association (JAMA) reports that women with these inherited mutations who have had a prophylactic mastectomy or salpingo-oophorectomy (removal of

Violence in Inner City Neighborhoods Contributes to Trouble With Asthma

Violence in Inner City Neighborhoods Contributes to Trouble With Asthma

PHILADELPHIA –   Patients with asthma who are exposed to violence in their community are at an increased risk for an asthma-related hospitalization and emergency room visits for asthma or any cause, according to new research from the University of Pennsylvania School of Medicine.

Jessica Mikulski

Penn Study Sheds Light on How the Brain Transitions Between Sleep and Awake States Under Anesthesia

Penn Study Sheds Light on How the Brain Transitions Between Sleep and Awake States Under Anesthesia

Despite the fact that an estimated 25 million patients per year in the U.S. undergo surgeries using general anesthesia, scientists have only been able to hypothesize exactly how anesthetics interact with the central nervous system. They previously thought that the processes of “going under” and waking up from anesthesia affected the brain in the same way.