Perelman School of Medicine

Researchers at the University of Pennsylvania School of Medicine, the Broad Institute, Massachusetts General Hospital, and Alnylam Pharmaceuticals Inc., are some of the first to prove that a gene linked to a disease trait by genome wide association studies (GWAS) can be clinically relevant and an important determinant of disease risk.

University of Pennsylvania School of Medicine researchers have described a previously unknown biological mechanism in cells that prevents them from cannibalizing themselves for fuel.

Investigators have found that fruit fly (Drosophila melanogaster) males -- in which the activity of an Alzheimer’s disease protein is reduced by 50 percent -- show impairments in learning and memory as they age.

AMP-activated protein kinase, or AMPK, is a master regulator protein of metabolism that is conserved from yeast to humans. When a cell is low on fuel, AMPK shuts down processes that use energy and turns on processes that produce energy.

Soccer referees may have an unconscious bias towards calling fouls based on a play’s direction of motion, according to a new study.

The Pew Charitable Trusts named Zhaolan (Joe) Zhou, PhD, assistant professor of Genetics at the University of Pennsylvania School of Medicine, as a 2010 Pew Scholar in the Biomedical Sciences.

PHILADELPHIA -– Harvey Rubin, executive director of the Institute for Strategic Threat Analysis and Response at the University of Pennsylvania, will be among the international experts participating in

Shiriki Kumanyika, PhD, MPH, professor of Epidemiology, has received an individual recognition award by the College of Physicians of Philadelphia, section on Public Health a

PHILADELPHIA - Using high-throughput sequencing to map the locations of a common type of jumping gene within a person’s entire genome, researchers at the University of Pennsylvania School of Medicine found extensive variation in these locations among the individuals they studied, further underscoring the role of these errant genes in maintaining genetic

PHILADELPHIA –- Genetic researchers from the University of Pennsylvania have combined data from existing archaeological and linguistic studies of Africa with human genetic data to shed light on the demographic history of the continent from which all human activity emerged.