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New microfluidic device delivers mRNA nanoparticles a hundred times faster
An etched silicon and glass wafer on a surface with a quarter beside it for scale.

The researchers’ new platform technology, called Very Large Scale Microfluidic Integration, allows tens of thousands of microfluidic units to be incorporated into a single three-dimensionally etched silicon-and-glass wafer. (Image: Penn Engineering Today)

New microfluidic device delivers mRNA nanoparticles a hundred times faster

With a “liquid assembly line,” Penn researchers have produced mRNA-delivering-nanoparticles significantly faster than standard microfluidic technologies.

Evan Lerner

Vaccine lotteries and beyond: What motivates healthy behaviors
Sprinkle donuts falling from sky over a vial of vaccine and a needle.

Vaccine lotteries and beyond: What motivates healthy behaviors

As COVID-19 vaccines have become available to the general public and vaccination rates began to slow, there has been a boom in incentives for receiving the vaccine across the United States. CHIBE’s Kevin Volpp investigates the trend.

From Penn Medicine News

Lipids model how to explore for unexpected diseases
Lipid panel with check marks with a stethoscope resting on top of the file.

Lipids model how to explore for unexpected diseases

Lipids are known heritable risk factors for cardiovascular disease, but increasing evidence also supports shared genetics with diseases of other organ systems.

From Penn Medicine News

The pandemic, health inequities, and an ‘opportunity for change’
covid global map

As a global pandemic, COVID-19 spread across the world. But it didn’t hit everyone equally. “Being healthy is essential to human flourishing,” says Jennifer Prah Ruger, who advocates for shared norms in health governance to address global inequalities. (Image: Martin Sanchez, also featured on homepage)

The pandemic, health inequities, and an ‘opportunity for change’

Experts across the University weigh in on which lessons the pandemic drove home and what immediate measures are needed to prevent future loss.
With remarkable similarities to MS, a disease in dogs opens new avenues for study
Microscopic image of cells labeled blue, green, and pink

A naturally occurring canine disease called granulomatous meningoencephalomyelitis replicates many features of multiple sclerosis, including the involvement of B cells (in red) and T cells (green) in the tissues that line the central nervous system. (Image: Penn Vet)

With remarkable similarities to MS, a disease in dogs opens new avenues for study

Researchers at the School of Veterinary Medicine led by Jorge Iván Alvarez and Molly Church found that the canine disease granulomatous meningoencephalomyelitis shares many of the same pathological and immunological features as MS.

Katherine Unger Baillie

Penn mRNA pioneers receive the Princess of Asturias Award
Two people seated at a table in front of a panel that reads "Penn Medicine" many times over. The person on the left is wearing a gray suit, with a white shirt and red tie. The person on the right is wearing glasses, an orange shirt, and a black cardigan.

Drew Weissman (left) is the Roberts Family Professor of Vaccine Research in the Perelman School of Medicine. Katalin Karikó is an adjunct professor of Neurosurgery at Penn and a senior vice president at BioNTech. (Image: Penn Medicine)

Penn mRNA pioneers receive the Princess of Asturias Award

Drew Weissman and Katalin Karikó earned the prestigious honor for their foundational research that led to development of two lifesaving mRNA COVID-19 vaccines.

From Penn Medicine News

How mRNA vaccines help fight cancer tumors
gloved hand holding covid vacciine

How mRNA vaccines help fight cancer tumors

Penn researchers are looking to mRNA vaccines for applications outside of infectious diseases, as they can not only prompt strong antibody responses to fight off invaders, like COVID-19, but also potent cytotoxic T cell responses.

Steve Graff