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Penn Engineers Develop the “WorMotel,” Simultaneously Study the Aging Process in Thousands of Model Organisms

Penn Engineers Develop the “WorMotel,” Simultaneously Study the Aging Process in Thousands of Model Organisms

The roundworm C. elegans is one of the most important model organisms in biological research. With a transparent, millimeter-long body containing only about a thousand cells and a lifespan of a few weeks, there is no better way of deciphering the role of a given gene on a living creature’s anatomy or behavior.

Evan Lerner , Ali Sundermier

Penn Summer Program in STEM Teaches Middle Schoolers to Overcome Communication Barriers

Penn Summer Program in STEM Teaches Middle Schoolers to Overcome Communication Barriers

Mark Licurse didn’t know what to expect when he decided to group together middle schoolers from two very different schools for a week-long STEM Summer Science Camp held by the Laboratory for Research on the Structure of Matter at the University of Pennsylvania.

Ali Sundermier

These small robots are inspired by origami
Sung is developing design software to enable people without an engineering background to create custom origami robots that can move on the ground. The tool, called Interactive Robogami, is based on a database of robot parts which users can combine together like a “virtual Lego set.”

Sung is developing design software to enable people without an engineering background to create custom origami robots that can move on the ground. The tool, called Interactive Robogami, is based on a database of robot parts which users can combine together like a “virtual Lego set.”

These small robots are inspired by origami

Through origami-inspired engineering, one researcher hopes to not only create rapidly fabricable robots, but also build intuitive design software that enables others who may not be trained in engineering to create their own personalized robots.

Ali Sundermier

Penn Engineers Identify Protein Implicated in 3-D Epigenetics of Brain Development

Penn Engineers Identify Protein Implicated in 3-D Epigenetics of Brain Development

The vast majority of genetic mutations that are associated with disease occur at sites in the genome that aren’t genes. These sequences of DNA don’t code for proteins themselves, but provide an additional layer of instructions that determine if and when particular genes are expressed.

Evan Lerner , Ali Sundermier

Penn Researchers Engineer Macrophages to Engulf Cancer Cells in Solid Tumors

Penn Researchers Engineer Macrophages to Engulf Cancer Cells in Solid Tumors

One reason cancer is so difficult to treat is that it avoids detection by the body. Agents of the immune system are constantly checking the surfaces of cells for chemical signals that say they belong, but cancer cells express the same chemical signals as healthy ones. Without a way for the immune system to tell the difference, little stands in the way of cancer taking over.

Evan Lerner , Ali Sundermier