School of Veterinary Medicine

In a new effort, researchers from the University of Pennsylvania and Baylor College of Medicine have used advanced imaging technology to fill in details about the underlying cause of canine diabetes, which until now has been little understood.

Just as the brain forms memories of familiar faces, the immune system remembers pathogens it has encountered in the past. T cells with these memories circulate in the blood stream looking for sites of new infection.

The human genome encodes roughly 20,000 genes, only a few thousand more than fruit flies. The complexity of the human body, therefore, comes from far more than just the sequence of nucleotides that comprise our DNA, it arises from modifications that occur at the level of gene, RNA and protein.

Cancer cells defy the rules by which normal cells abide. They can divide without cease, invade distant tissues and consume glucose at abnormal rates.

In the most severe form of male infertility, men do not make any measurable levels of sperm. This condition, called azoospermia, affects approximately 1 percent of the male population and is responsible for about a sixth of cases of male infertility.

For diabetics, a quick prick of the finger can give information about their blood glucose levels, guiding them in whether to have a snack or inject a dose of insulin. Point-of-care glucose meters, or glucometers, are also used in the veterinary world to monitor cats and dogs with diabetes or pets hospitalized for other reasons.

Stress during the first trimester of pregnancy alters the population of microbes living in a mother’s vagina. Those changes are passed on to newborns during birth and are associated with differences in their gut microbiome as well as their brain development, according to a new study by University of Pennsylvania researchers.

Cattle in the United States are generally managed to either produce milk or to produce beef. However, in most of the world, cattle are counted on to do both in what are called dual-purpose production systems.

Researchers from the University of Pennsylvania and Michigan State University presented new preclinical data this week that evaluates the efficacy of a gene therapy treatment for achromatopsia, a rare inherited retinal disease that involves cone cells. The disease affects humans as well as dogs.

Like a beloved pair of jeans, human DNA accumulates damage over time, and older people’s bodies can’t repair it as well. Many scientists believe a build up of damage can cause cells to enter an irreversible dormant state known as senescence.