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School of Veterinary Medicine

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A Penn Vet tale: Olive, the tiny little fighter
A small wide-eyed Shi Tzu holds large boxing gloves in its mouth.

Illustration by Jon Krause.

A Penn Vet tale: Olive, the tiny little fighter

When Olive, the four-month-old Shih Tzu mix, became critically ill with respiratory distress, clinicians at Penn Vet’s Ryan Hospital spent a week collaborating on intensive treatment.

Sacha Adorno

A heart start for Milkshake, the fainting goat
A veterinarian checks a fainting goats heart rate in a vet office.

Laurence Leduc performs an ultrasound on Milkshake during a follow-up appointment. (Image: Penn Vet News)

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A heart start for Milkshake, the fainting goat

When Milkshake’s vitals were dangerously compromised, a team at Penn Vet’s New Bolton Center pinpointed the problem in the fainting goat’s heart, and saved her life.

From Penn Vet

Elucidating the developmental origin of life-sustaining adrenal glands
microscopic image with proteins labeled in red and blue shows tissue that develops into the adrenal glands

The adrenal glands, which pump out crucial hormones, develops differently in mice compared to primates, including humans, according to new research led by the School of Veterinary Medicine. At at early stage of development, the primate adrenogenic coelomic epithelium, which eventually gives rise to the adrenal glands, expresses genes (NR5A1 in red, and GATA1 in blue) in a pattern that diverged with expectations. (Image: Kotaro Sasaki)

Elucidating the developmental origin of life-sustaining adrenal glands

Research led by the School of Veterinary Medicine reveals that adrenal development proceeds differently in humans than it does in mice.

Katherine Unger Baillie

Frozen testicular tissue still viable after 20 years
Cross-section of testes tissue shows a variety of cells labeled pink and blue and sperm

After being transferred to an infertile mouse, testes tissue from a rat that had been frozen for more than two decades gave rise to sperm and germ cells. (Image: Eoin Whelan/PLOS Biology/CC-BY 4.0 https://creativecommons.org/licenses/by/4.0)

Frozen testicular tissue still viable after 20 years

Many pediatric cancer treatments, though lifesaving, can compromise future fertility. In a new study in rodents, researchers from the School of Veterinary Medicine showed that testicular tissue frozen for more than 20 years could give rise to sperm.

Katherine Unger Baillie

Symposium highlights range and reach of Penn Global research
Panelists sit on a stage at Perry World House, while another is on a Zoom screen behind them

The 2022 Launch Symposium at Perry World House brought together faculty from eight of Penn’s 12 schools to share presentations on their projects that span the globe.

Symposium highlights range and reach of Penn Global research

The Penn Global Research and Engagement Grant is supporting 21 faculty-led projects that span research, capacity-building, and development efforts across Africa, Latin America and the Caribbean, India, China, and beyond.

Kristen de Groot

In the Galápagos, training community scientists to monitor water quality
Group poses in a tropical marine landscape holding a sign that reads Allianza para la Educaion e Investigacion en Galapagos

Under the umbrella of the Galápagos Education and Research Alliance, Penn Vet professor Daniel Beiting (far right) and others from Penn visited San Cristóbal Island in March, where they engaged students and scientists in water quality testing. (Image: Courtesy of Daniel Beiting)

In the Galápagos, training community scientists to monitor water quality

Both dense human populations and a plethora of wildlife can pose a challenge to marine and public health in the Galápagos Islands. With portable, user-friendly PCR technology, Penn faculty and students are training local scientists and school children to perform water quality research.

Katherine Unger Baillie

Regulating the regulators of the immune system
T cells labeled in fluorescent green patrol the vascular system, labeled in red

Regulating the regulators of the immune system

Research led by School of Veterinary Medicine scientists reveals a new layer of complexity with which the immune system finds a balance between controlling pathogens and protecting healthy tissue.

Katherine Unger Baillie

Revising the lifecycle of an important human parasite
Black and white microscopic image of many cells clustered tightly

The parasite Cryptosporidium, transmitted through water sources, is one of the most common causes of diarrheal disease in the world. (Image: Muthgapatti Kandasamy and Boris Striepen)

Revising the lifecycle of an important human parasite

Researchers from Boris Striepen’s lab in the School of Veterinary Medicine tracked Cryptosporidium in real time, creating a new paradigm for how the widespread parasite reproduces in a host.

Katherine Unger Baillie

Correcting night blindness in dogs
Three panels show fluorescent images of therapeutic gene LRIT3, which corrects a form of night blindness

Correcting night blindness in dogs

Researchers in the School of Veterinary Medicine and colleagues have developed a gene therapy that restores dim-light vision in dogs with a congenital form of night blindness, offering hope for treating a similar condition in people.

Katherine Unger Baillie

From a pandemic, scientific insights poised to impact more than just COVID-19
emulsions of oil and water separated by a layer of nanoparticles.

Bijels, or bicontinuous interfacially jammed emulsion gels, are structured emulsions of oil and water that are kept separated by a layer of nanoparticles. Penn Engineering researchers will develop a way of using them to manufacture mRNA-based therapeutics. (Image: Penn Engineering Today)

From a pandemic, scientific insights poised to impact more than just COVID-19

Pivoting to study SARS-CoV-2, many scientists on campus have launched new research projects that address the challenges of the pandemic but also prepare us to confront future challenges.

Katherine Unger Baillie