Harnessing an innate protection against Ebola An innate mechanism in human cells may prevent Ebola virus from spreading, according to new Penn Vet-led research. Using powerful confocal microscopy, they tracked the budding of virus-like particles from cells (shown in the filamentous projections in the cell in the upper right) and how autophagy, a “self-eating” cellular process, by which viral proteins are sequestered in vesicles (shown in the cell in the lower left), inhibits virus-like particles from exiting. (Image: Courtesy of the Harty lab) Harnessing an innate protection against Ebola School of Veterinary Medicine researchers have identified a cellular pathway that keeps Ebola virus from exiting human cells, with implications for developing new antivirals.
Virology is part of the golden age of health: Don’t dismantle it The Hill Virology is part of the golden age of health: Don’t dismantle it James Alwine of the Perelman School of Medicine co-writes that over-regulation could unduly constrain the ability to respond to future viral pandemic threats. Coryza, an avian influenza lookalike, lingers in Lancaster Lancaster Farming Coryza, an avian influenza lookalike, lingers in Lancaster Sherrill Davison of the School of Veterinary Medicine outlines the symptoms and signs of infectious coryza, an avian influenza lookalike. Five things to know about this year’s ‘tripledemic’ Image: iStock/Srdjanns74 Five things to know about this year’s ‘tripledemic’ The Perelman School of Medicine’s E. John Wherry and Scott Hensley discuss the season’s confluence of COVID-19, influenza, and RSV and how our bodies are responding. How sex differences may influence lung injury AT2 cells, a type of lung cell that produces surfactant and give rise to gas-exchanging cells, can be infected by SARS-CoV-2. Research by Penn Vet scientists showed that differences in gene expression between male and female AT2 cells may help explain why older males have more severe outcomes from COVID-19 and similar diseases. (Image: Courtesy of the Anguera laboratory) How sex differences may influence lung injury Comparing lung cells from male and female mice, School of Veterinary Medicine scientists found gene expression differences that may explain why older males are at a higher risk than females for worse outcomes from COVID-19 and similar diseases. Penn scientists are honored for mRNA research used in COVID vaccines Philadelphia Inquirer Penn scientists are honored for mRNA research used in COVID vaccines Katalin Karikó and Drew Weissman of the Perelman School of Medicine have been named to the National Inventors Hall of Fame for their research on mRNA vaccines. COVID-19 is more widespread in animals than we thought National Geographic COVID-19 is more widespread in animals than we thought Frederic Bushman of the Perelman School of Medicine says that many mammalian ACE-2 receptors are proving susceptible to COVID, even if they aren’t a perfect match. What’s next for mRNA vaccines MIT Technology Review What’s next for mRNA vaccines Norbert Pardi of the Perelman School of Medicine and colleagues are developing a universal mRNA flu vaccine, featuring remarks from mRNA pioneer Katalin Karikó. New COVID variant drives increase in Pa. and N.J. infections Philadelphia Inquirer New COVID variant drives increase in Pa. and N.J. infections Frederic Bushman of the Perelman School of Medicine says that the new XBB.1.5 COVID variant is more immune-evasive and is sharply increasing in Pennsylvania as a proportion of all infections. Masks to temporarily return in Philadelphia and Camden school districts 6ABC.com Masks to temporarily return in Philadelphia and Camden school districts Terri Lipman of the School of Nursing says that masking remains one of the best ways to mitigate the high risk of COVID transmission in schools. Load More
Coryza, an avian influenza lookalike, lingers in Lancaster Lancaster Farming Coryza, an avian influenza lookalike, lingers in Lancaster Sherrill Davison of the School of Veterinary Medicine outlines the symptoms and signs of infectious coryza, an avian influenza lookalike. Five things to know about this year’s ‘tripledemic’ Image: iStock/Srdjanns74 Five things to know about this year’s ‘tripledemic’ The Perelman School of Medicine’s E. John Wherry and Scott Hensley discuss the season’s confluence of COVID-19, influenza, and RSV and how our bodies are responding. How sex differences may influence lung injury AT2 cells, a type of lung cell that produces surfactant and give rise to gas-exchanging cells, can be infected by SARS-CoV-2. Research by Penn Vet scientists showed that differences in gene expression between male and female AT2 cells may help explain why older males have more severe outcomes from COVID-19 and similar diseases. (Image: Courtesy of the Anguera laboratory) How sex differences may influence lung injury Comparing lung cells from male and female mice, School of Veterinary Medicine scientists found gene expression differences that may explain why older males are at a higher risk than females for worse outcomes from COVID-19 and similar diseases. Penn scientists are honored for mRNA research used in COVID vaccines Philadelphia Inquirer Penn scientists are honored for mRNA research used in COVID vaccines Katalin Karikó and Drew Weissman of the Perelman School of Medicine have been named to the National Inventors Hall of Fame for their research on mRNA vaccines. COVID-19 is more widespread in animals than we thought National Geographic COVID-19 is more widespread in animals than we thought Frederic Bushman of the Perelman School of Medicine says that many mammalian ACE-2 receptors are proving susceptible to COVID, even if they aren’t a perfect match. What’s next for mRNA vaccines MIT Technology Review What’s next for mRNA vaccines Norbert Pardi of the Perelman School of Medicine and colleagues are developing a universal mRNA flu vaccine, featuring remarks from mRNA pioneer Katalin Karikó. New COVID variant drives increase in Pa. and N.J. infections Philadelphia Inquirer New COVID variant drives increase in Pa. and N.J. infections Frederic Bushman of the Perelman School of Medicine says that the new XBB.1.5 COVID variant is more immune-evasive and is sharply increasing in Pennsylvania as a proportion of all infections. Masks to temporarily return in Philadelphia and Camden school districts 6ABC.com Masks to temporarily return in Philadelphia and Camden school districts Terri Lipman of the School of Nursing says that masking remains one of the best ways to mitigate the high risk of COVID transmission in schools. Load More
Five things to know about this year’s ‘tripledemic’ Image: iStock/Srdjanns74 Five things to know about this year’s ‘tripledemic’ The Perelman School of Medicine’s E. John Wherry and Scott Hensley discuss the season’s confluence of COVID-19, influenza, and RSV and how our bodies are responding.
How sex differences may influence lung injury AT2 cells, a type of lung cell that produces surfactant and give rise to gas-exchanging cells, can be infected by SARS-CoV-2. Research by Penn Vet scientists showed that differences in gene expression between male and female AT2 cells may help explain why older males have more severe outcomes from COVID-19 and similar diseases. (Image: Courtesy of the Anguera laboratory) How sex differences may influence lung injury Comparing lung cells from male and female mice, School of Veterinary Medicine scientists found gene expression differences that may explain why older males are at a higher risk than females for worse outcomes from COVID-19 and similar diseases.
Penn scientists are honored for mRNA research used in COVID vaccines Philadelphia Inquirer Penn scientists are honored for mRNA research used in COVID vaccines Katalin Karikó and Drew Weissman of the Perelman School of Medicine have been named to the National Inventors Hall of Fame for their research on mRNA vaccines. COVID-19 is more widespread in animals than we thought National Geographic COVID-19 is more widespread in animals than we thought Frederic Bushman of the Perelman School of Medicine says that many mammalian ACE-2 receptors are proving susceptible to COVID, even if they aren’t a perfect match. What’s next for mRNA vaccines MIT Technology Review What’s next for mRNA vaccines Norbert Pardi of the Perelman School of Medicine and colleagues are developing a universal mRNA flu vaccine, featuring remarks from mRNA pioneer Katalin Karikó. New COVID variant drives increase in Pa. and N.J. infections Philadelphia Inquirer New COVID variant drives increase in Pa. and N.J. infections Frederic Bushman of the Perelman School of Medicine says that the new XBB.1.5 COVID variant is more immune-evasive and is sharply increasing in Pennsylvania as a proportion of all infections. Masks to temporarily return in Philadelphia and Camden school districts 6ABC.com Masks to temporarily return in Philadelphia and Camden school districts Terri Lipman of the School of Nursing says that masking remains one of the best ways to mitigate the high risk of COVID transmission in schools. Load More
COVID-19 is more widespread in animals than we thought National Geographic COVID-19 is more widespread in animals than we thought Frederic Bushman of the Perelman School of Medicine says that many mammalian ACE-2 receptors are proving susceptible to COVID, even if they aren’t a perfect match. What’s next for mRNA vaccines MIT Technology Review What’s next for mRNA vaccines Norbert Pardi of the Perelman School of Medicine and colleagues are developing a universal mRNA flu vaccine, featuring remarks from mRNA pioneer Katalin Karikó. New COVID variant drives increase in Pa. and N.J. infections Philadelphia Inquirer New COVID variant drives increase in Pa. and N.J. infections Frederic Bushman of the Perelman School of Medicine says that the new XBB.1.5 COVID variant is more immune-evasive and is sharply increasing in Pennsylvania as a proportion of all infections. Masks to temporarily return in Philadelphia and Camden school districts 6ABC.com Masks to temporarily return in Philadelphia and Camden school districts Terri Lipman of the School of Nursing says that masking remains one of the best ways to mitigate the high risk of COVID transmission in schools. Load More
What’s next for mRNA vaccines MIT Technology Review What’s next for mRNA vaccines Norbert Pardi of the Perelman School of Medicine and colleagues are developing a universal mRNA flu vaccine, featuring remarks from mRNA pioneer Katalin Karikó. New COVID variant drives increase in Pa. and N.J. infections Philadelphia Inquirer New COVID variant drives increase in Pa. and N.J. infections Frederic Bushman of the Perelman School of Medicine says that the new XBB.1.5 COVID variant is more immune-evasive and is sharply increasing in Pennsylvania as a proportion of all infections. Masks to temporarily return in Philadelphia and Camden school districts 6ABC.com Masks to temporarily return in Philadelphia and Camden school districts Terri Lipman of the School of Nursing says that masking remains one of the best ways to mitigate the high risk of COVID transmission in schools. Load More
New COVID variant drives increase in Pa. and N.J. infections Philadelphia Inquirer New COVID variant drives increase in Pa. and N.J. infections Frederic Bushman of the Perelman School of Medicine says that the new XBB.1.5 COVID variant is more immune-evasive and is sharply increasing in Pennsylvania as a proportion of all infections. Masks to temporarily return in Philadelphia and Camden school districts 6ABC.com Masks to temporarily return in Philadelphia and Camden school districts Terri Lipman of the School of Nursing says that masking remains one of the best ways to mitigate the high risk of COVID transmission in schools. Load More
Masks to temporarily return in Philadelphia and Camden school districts 6ABC.com Masks to temporarily return in Philadelphia and Camden school districts Terri Lipman of the School of Nursing says that masking remains one of the best ways to mitigate the high risk of COVID transmission in schools.