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mRNA Research
The long view on COVID-19 vaccine safety and efficacy
The long view on COVID-19 vaccine safety and efficacy
Penn researchers weigh in on the regulatory and scientific efforts to track COVID-19 vaccines.
New microfluidic device delivers mRNA nanoparticles a hundred times faster
New microfluidic device delivers mRNA nanoparticles a hundred times faster
With a “liquid assembly line,” Penn researchers have produced mRNA-delivering-nanoparticles significantly faster than standard microfluidic technologies.
The pandemic, health inequities, and an ‘opportunity for change’
The pandemic, health inequities, and an ‘opportunity for change’
Experts across the University weigh in on which lessons the pandemic drove home and what immediate measures are needed to prevent future loss.
Penn mRNA pioneers receive the Princess of Asturias Award
Penn mRNA pioneers receive the Princess of Asturias Award
Drew Weissman and Katalin Karikó earned the prestigious honor for their foundational research that led to development of two lifesaving mRNA COVID-19 vaccines.
How mRNA vaccines help fight cancer tumors
How mRNA vaccines help fight cancer tumors
Penn researchers are looking to mRNA vaccines for applications outside of infectious diseases, as they can not only prompt strong antibody responses to fight off invaders, like COVID-19, but also potent cytotoxic T cell responses.
In the vaccine trenches with Katalin Kariko and Drew Weissman
In the vaccine trenches with Katalin Kariko and Drew Weissman
Key breakthroughs leading to the powerful mRNA vaccines against COVID-19 were forged at Penn, and the COVID-19 vaccines may only be the beginning of its impact on 21st-century medicine.
Researchers identify potential nanoparticles for therapeutic mRNA delivery before birth
Researchers identify potential nanoparticles for therapeutic mRNA delivery before birth
Researchers at Children’s Hospital of Philadelphia and the School of Engineering and Applied Science have identified ionizable lipid nanoparticles that could be used to deliver mRNA as part of fetal therapy.
Translating groundbreaking scientific discoveries into practical technologies
Amidst the numerous challenges posed by COVID-19, the Penn Center for Innovation has continued to facilitate impactful innovations created at Penn, fostering partnerships and helping to realize new products and businesses.
Five things to know about the promising COVID-19 vaccine news
Five things to know about the promising COVID-19 vaccine news
Drew Weissman of the Perelman School of Medicine, whose work is a key factor helping to enable two vaccines in late stages of testing, sheds light on the biology behind them and on his predictions about next steps in vaccine development and approval.
Penn nanoparticles are less toxic to T cells engineered for cancer immunotherapy
Penn nanoparticles are less toxic to T cells engineered for cancer immunotherapy
By using messenger RNA across the T cell’s membrane via a nanoparticle instead of a DNA-rewriting virus on extracted T cells, CAR T treatments could have fewer side effects.
In the News
The Hill
mRNA vaccine by UPenn scientists could manage bird flu outbreak
Researchers led by Scott Hensley of the Perelman School of Medicine have collaborated with Drew Weissman to develop an mRNA vaccine to treat the H5N1 avian flu.
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6ABC.com
Penn Medicine creates human bird flu vaccine
Researchers at Penn Medicine have created a human bird flu vaccine using mRNA, the same platform as the COVID-19 vaccine.
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Fast Company
Researchers are working on a new mRNA vaccine—this time for bird flu
Researchers led by Scott Hensley of the Perelman School of Medicine are developing an mRNA vaccine for the H5N1 avian flu with support from Nobel Prize cowinner Drew Weissman.
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Deutsche Welle
A vaccine for pancreatic cancer?
Drew Weissman of the Perelman School of Medicine comments on the efficacy of a potential pancreatic cancer vaccine.
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Scientific American
Pancreatic cancer vaccine shows promise in small initial trial
Drew Weissman of the Perelman School of Medicine is supportive of findings about a pancreatic cancer vaccine, though he says larger studies are needed to determine effectiveness.
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