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Karen Kreeger
Anti-Inflammatory, Anti-Cell Death Agent a Potential Treatment for Vision Loss Associated with Multiple Sclerosis
A new therapeutic agent tested in a mouse model of multiple sclerosis (MS) produced anti-inflammatory activity and prevented loss of cells in the optic nerve, according to a new study by researchers in the Perelman School of Medicine at the University of Pennsylvania, with Pittsburgh-based Noveome Biotherapeutics.
Karen Kreeger ・
Penn Medicine: “Mysterious” Non-protein-coding RNAs Play Important Roles In Gene Expression
In cells, DNA is transcribed into RNAs that provide the molecular recipe for cells to make proteins. Most of the genome is transcribed into RNA, but only a small proportion of RNAs are actually from the protein-coding regions of the genome.
Karen Kreeger ・
Penn Medicine: Evidence of Alzheimer's in Patients with Lewy Body Disease Tracks with Course of Dementia
Patients who had a diagnosis of Parkinson’s disease (PD) with dementia (PDD) or dementia with Lewy bodies (DLB) and had higher levels of Alzheimer’s disease (AD) pathology in their donated post-mortem brains also had more severe symptoms of these Lewy body diseases (LBD) during their lives, compared to those whose brains had less AD pathology, according to research from the
Karen Kreeger ・
Linking Human Genome Sequences to Health Data Will Change Clinical Medicine, says Penn Expert
The value of intersecting the sequencing of individuals’ exomes (all expressed genes) or full genomes to find rare genetic variants -- on a large scale -- with their detailed electronic health record (EHR) information has “myriad benefits, including the illumination of basic human biology, the early identification of preventable and treatable illnesses, and the identification and validation of
Karen Kreeger ・
Penn Immunotherapy Pioneer Elected to National Academy of Inventors
Yvonne J. Paterson, PhD, a professor of Microbiology in the Perelman School of Medicine at the University of Pennsylvania, has been elected a fellow of the National Academy of Inventors. Fellows are named inventors on U.S.
Karen Kreeger ・
Ten Penn Professors Named AAAS Fellows for 2016
Ten professors from the University of Pennsylvania have been named Fellows of the American Association for the Advancement of Science. They are among a class of 391 members honored for their scientifically or socially distinguished efforts to advance science or its applications.
Katherine Unger Baillie, Karen Kreeger ・
Penn Cell Biologist Awarded $5.2 Million from NIH for Lung Regeneration Research
Penn Medicine researchers, along with colleagues at Cincinnati Children's Hospital and Boston University, have received a $5.2 million, seven-year grant from the National Heart, Lung, and Blood Institute of the National Institutes of Health (NIH) to study the cellular and molecular mechanisms that promote lung regeneration.
Karen Kreeger ・
Penn Scientists Receive $24 Million from National Science Foundation to Establish Mechanobiology Center
The National Science Foundation (NSF) has awarded the University of Pennsylvania a $24 Million, five-year grant to establish a Science and Technology Center (STC) focused on engineering mechanobiology, or the way cells exert and are influenced by the physical forces in their environment. This award is part of an overall $94 million from NSF to support four new STCs.
Karen Kreeger, Evan Lerner ・
Penn Medicine: Fatty Diet Activates Oldest Branch of Immune System, Causing Intestinal Tumors
A high-fat-diet-induced immune reaction causes inflammation leading to intestinal cancer in a mouse model – even among animals that are not obese -- according to a new study from thePerelman School of Medicine at the University of Pennsylvania, Case Western Reser
Karen Kreeger ・
Penn Medicine: New Mouse Model Points to Drug Target Potentially Useful for Increasing Social Interaction in Autism
A study of a new mouse model identifies a drug target that has the potential to increase social interaction in individuals with some forms of autism spectrum disorder (ASD), according to researchers in the Perelman School of Medicine at the University of Pennsylvania.
Karen Kreeger ・