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If you’ve ever wondered how a vaccine given decades ago can still protect against infection, you have your plasma cells to thank. Plasma cells are long-lived B cells that reside in the bone marrow and churn out antibodies against previously encountered vaccines or pathogens.
A weapon, whether a body part such as hands, fists and feet or an external instrument like a gun, often accompanies intimate-partner violence. Susan B.
Casting one of the largest genomic nets to date for the rare tumors of the autonomic nervous system known as pheochromocytoma and paraganglioma (PCC/PGL) captured several new mutations driving the disease that could serve as potential drug targets, researchers from Penn Medicine and other institutions reported in
Penn Medicine’s Orphan Disease Center (ODC) announces a new partnership with the Foundation for Angelman Syndrome Therapeutics or FAST to study gene therapy approaches to treat Angelman syndrome (AS).
People with hemophilia require regular infusions of clotting factor to prevent them from experiencing uncontrolled bleeding. But a significant fraction develop antibodies against the clotting factor, essentially experiencing an allergic reaction to the very treatment that can prolong their lives.
Critically ill infants and children do not gain extra benefit from lower blood-sugar levels, compared to higher levels within the usual care range, according to research from the Children’s Hospital of Philadelphia, the University of Pennsylvania
A new therapeutic agent tested in a mouse model of multiple sclerosis (MS) produced anti-inflammatory activity and prevented loss of cells in the optic nerve, according to a new study by researchers in the Perelman School of Medicine at the University of Pennsylvania, with Pittsburgh-based Noveome Biotherapeutics.
Katalin Susztak, MD, PhD, an associate professor of Medicine and Genetics in the Perelman School of Medicine at the University of Pennsylvania, has received a $3 million grant from a consortium of pharmaceutical companies to identify genes and other characteristics that are signs of rapid decline in kidney function in patients with diabetic kidney disease.
A new Zika vaccine candidate has the potential to protect against the virus with a single dose, according to a research team led by scientists from the Perelman School of Medicine at the University of Pennsylvania. As reported in Nature this week, preclinical tests showed promising immune responses in both mice and monkeys.
Depending on the specific type, bacteria in a woman’s vagina and cervix may increase the risk of premature birth or protect against it, according to new research from the Perelman School of Medicine at the University of Pennsylvania.
According to Aditi Vasan of the Leonard Davis Institute and Perelman School of Medicine, evidence is mounting in favor of the model of training community health workers to help their neighbors connect to government and health care services.
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Lauren Massimo of the School of Nursing says that losing the ability to drive is a major and dehumanizing loss for older adults.
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According to Thomas Wadden of the Perelman School of Medicine, people taking GLP-1 drugs are finding that daily experiences that used to trigger a compulsion to eat or think about food no longer have that effect.
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The Eidos LGBTQ+ Health Initiative, led by José Bauermeister and Jessica Halem of the School of Nursing, will host a free online panel in April on the integration of LGBTQ+ people in the workforce.
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PIK Professor Ezekiel Emanuel says that incessantly preparing for old age mistakes a long life for a worthwhile one.
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