The team looked at measurements of cortical thickness in the brain, an indicator of brain atrophy usually due to loss of neurons or their connections. Using MRI scans, they measured cortical thickness in several brain regions that had previously been shown to be associated with the injury due to early Alzheimer’s disease. In this case, these measurements were obtained in cognitively normal adults who were followed over time, allowing the researchers to assess whether cortical thinning in these regions tracked with their cognitive abilities.
Nanoparticle blueprints reveal path to smarter medicines
New research involving Penn Engineering shows detailed variation in lipid nanoparticle size, shape, and internal structure, and finds that such factors correlate with how well they deliver therapeutic cargo to a particular destination.
A generous gift from alumni Glenn and Amanda Fuhrman brings the work of internationally acclaimed artist Jaume Plensa to the University of Pennsylvania. The latest addition to the Penn Art Collection expands Philadelphia's public art.
A massive chunk of ice, a new laser, and new information on sea-level rise
For nearly a decade, Leigh Stearns and collaborators aimed a laser scanner system at Greenland’s Helheim Glacier. Their long-running survey reveals that Helheim’s massive calving events don’t behave the way scientists once thought, reframing how ice loss contributes to sea-level rise.
