First Microscopic Video of Blood Clot Contraction Reveals How Platelets Naturally Form Unobtrusive Clots

The first view of the physical mechanism of how a blood clot contracts at the level of individual platelets is giving researchers from the Perelman School of Medicine at the University of Pennsylvania a new look at a natural process that is part of blood clotting. A team led by John W.

Karen Kreeger

Penn Study Links Mutations in Notch Gene to Role in B Cell Cancers

Notch is one of the most frequently mutated genes in chronic lymphocytic leukemia (CLL), the most common leukemia in adults in the United States. It is also often mutated in other common B cell tumors, such as mantle cell lymphoma. However, the role of Notch in these cancers has been uncertain.

Karen Kreeger

Seven Penn Faculty Members Elected to National Academy of Medicine

Seven University of Pennsylvania faculty members have been elected to the National Academy of Medicine (NAM), one of the nation’s highest honors in biomedicine. They are among 70 new U.S. and 10 international members of the globally renowned organization.

Karen Kreeger, Michele W. Berger

Melanoma Cells Rewire to Resist Drug Treatment, Penn-Wistar Team Finds

In 2014, new combination therapies to treat patients with metastatic melanoma hit the market, helping extend the lives of those with this aggressive disease. Yet unfortunately, after several months of treatment, almost all patients on the regimen eventually relapsed.

Katherine Unger Baillie, Karen Kreeger, Darien Sutton

Penn Medicine Physiology Postdoctoral Researcher Named Hanna Gray Fellow

Chantell Evans, PhD, a postdoctoral fellow in the Perelman School of Medicine at the University of Pennsylvania, has been selected by the Howard Hughes Medical Institute (HHMI) as one of 15 early-career scientists in its first cohort of HHMI Hanna Gray Fellows.

Karen Kreeger