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By altering bone marrow, ‘training’ can prepare innate immune system for future challenges
George Hajishengallis of the School of Dental Medicine and an international team of colleagues have found that “training” the immune system causes changes in the precursors of immune cells in the bone marrow. These changes could facilitate a more robust response to future infections or even enable the immune system to regenerate faster after chemotherapy.
Pets pick up on their owner’s personality
When a baby is born, many new moms and dads pore over parenting books, striving to strike the right balance of firmness and warmth to raise their children into kind, intelligent, strong individuals. While nature plays a critical role, research supports the idea that parenting style and parents’ personalities do influence a child’s behavior.
5.5 million-year-old fossil turtle species sheds light on invasive modern relatives
A University of Pennsylvania paleontologist has described a 5.5 million-year-old fossil species of turtle from eastern Tennessee. It represents a new species of the genus Trachemys, commonly known as sliders, which are frequently kept as pets today.
Low-calorie diet enhances intestinal regeneration after injury
Dramatic calorie restriction, diets reduced by 40 percent of a normal calorie total, have long been known to extend health span, the duration of disease-free aging, in animal studies, and even to extend life span in most animal species examined.
New open-access data resource aims to bolster collaboration in global infectious disease research
Population-based epidemiological studies provide new opportunities for innovation and collaboration among researchers addressing pressing global-health concerns.
Tracking birds in flight over the Philadelphia skies
Each spring and fall, birds take wing on journeys of thousands of miles, seeking prime breeding habitats or safe and comfortable places to ride out the winter.
More than flowers and food, campus garden grows community
By mid-February, winter’s freezing temperatures and drab landscapes can seem like they will last forever. But for at least one staff member at Penn, spring’s verdant bounty is never far from her mind.
Study uncovers therapeutic targets for aggressive triple-negative breast cancers
As part of a breast-cancer diagnosis, doctors analyze the tumor to determine which therapies might best attack the malignancy. But for patients whose cancer is triple-negative — that is, lacking receptors for estrogen, progesterone and Her2 — the options for treatment dwindle. Triple-negative cancers, or TNBC, also tend to be more aggressive than other cancer subtypes.
A new hope for treating triple-negative breast cancer
Breast cancer mortality rates have steadily declined over the past few decades, thanks to a combination of early detection and improved treatments. But for patients diagnosed with triple-negative breast cancer (TNBC), a subtype in which tumor cells lack receptors for estrogen, progesterone, and Her2, no targeted treatments are available.