Armored CAR T cells break through immune suppression in solid tumors
A study by Joseph Fraietta of the Perelman School of Medicine and colleagues found a way to “armor” CAR T cells, enabling them to get past immunosuppressors in prostate cancer.
A study by Joseph Fraietta of the Perelman School of Medicine and colleagues found a way to “armor” CAR T cells, enabling them to get past immunosuppressors in prostate cancer.
A study from Shuying (Sheri) Yang of the School of Dental Medicine and colleagues identified a protein that regulates osteoclasts, the cells that break down bone, which may pave the way for new treatments that prevent bone loss.
Robert Stuart-Smith of the Weitzman School of Design and colleagues demonstrate how 3D-printing drones can create large structures made of foam or cement, paving the way for future construction efforts.
In Drew Weissman’s lab at the Perelman School of Medicine, researchers like Mohamad-Gabriel Alameh, Benjamin Davis, and Garima Dwivedi are developing pan-coronavirus vaccines to guard against future variants.
Richard W. Vague Professor in Immunotherapy Carl June.
Mindy and Jon Gray’s new Basser Institute is a spinoff of their previously funded Basser Center for BRCA, named for Mindy’s late sister Faith Basser and led by Susan Domchek of the Perelman School of Medicine.
Capstan Therapeutics, a Penn spinout whose founders include Carl June, Bruce Levine, and Drew Weissman of the Perelman School of Medicine, has launched with $165 million raised to develop a new type of CAR therapy that incorporates mRNA.
A multidisciplinary Penn team including Michael Koo of the School of Dental Medicine and Edward Steager of the School of Engineering and Applied Science has created an automated way to brush and floss through robotics, a potentially useful development for those unable to clean their teeth themselves.
A study by Casey Halpern of the Perelman School of Medicine suggests that the impulse control associated with binge eating disorder stems from brain neurology, not a moral failing.