Perelman School of Medicine

For aging patients, one missed doctor’s visit can lead to vision loss

A Penn Medicine study found keeping regular ophthalmology appointments play an important role in outcomes for patients with age-related macular degeneration.

St. Bernard dog with three legs sits outside near a pile of firewood

Treatment in a FLASH

A clinical trial in dogs with cancer, co-led by the Perelman School of Medicine and the School of Veterinary Medicine, is testing the feasibility, safety, and effectiveness of delivering a full dose of radiation therapy in a split second.

rendering of DNA sequence and cells as part of gene editing from CRISPR cas9

CRISPR-edited immune cells can survive and thrive after infusion into cancer patients

In the first U.S. clinical trial, cells removed from patients and brought back into the lab were able to kill cancer months after their original manufacturing and infusion.

A group of people talking and laughing in a cluster, with a video camera being held in the top left corner.

Meet the biology major who brought an Iowa caucus to Philadelphia

Junior Jessica Anderson organized the satellite event because she wanted to participate in the political process. Politics aside, she’s aiming for a career that combines research and patient care.

A CAR T cell interacting with a cancer cell

Defect driving resistance to CAR T therapy identified

A new study identifies the mechanism that prevents cell death, and can guide future immunotherapy strategies in patients whose blood cancers are resistant to CAR T therapy.

An artist’s illustration of nanoparticles transporting mRNA into a T cell, allowing the latter to express surface receptors that recognize cancer cells.

Penn nanoparticles are less toxic to T cells engineered for cancer immunotherapy

By using messenger RNA across the T cell’s membrane via a nanoparticle instead of a DNA-rewriting virus on extracted T cells, CAR T treatments could have fewer side effects.

People in a subway station in Shanghai wearing surgical masks. One is carrying two bags, another is carrying a phone, a third is holding an umbrella.

What we do and don’t know about the novel coronavirus

Experts from the Vet School, Med School, and Center for Public Health Initiatives provide insight into the new disease outbreak.

Closeup of hands on a person's chest performing chest compressions outdoors

Bystander CPR less likely for people living in Hispanic neighborhoods

A Penn study shows residents of Hispanic neighborhoods also have a lower chance of survival following cardiac arrest compared to those living in non-Hispanic neighborhoods.

Infant lying on their back with a doctor and nurse standing above with a vaccine injection

New vaccines to protect infants from infections

A new Penn Medicine study puts researchers within closer reach of vaccines that can protect infants against infections by overcoming a mother’s antibodies.

Lab-grown brain organoids, rapidly deployed, can fight glioblastomas

Glioblastoma organoids grown from patients’ own glioblastoma tissue can be used to investigate personalized treatment approaches in time-sensitive cases.

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