In pursuit of a cure, when ideas and options have run out David Fajgenbaum is an assistant professor of medicine at the Perelman School of Medicine at the University of Pennsylvania and associate director of patient impact in the Penn Orphan Disease Center. He also leads the Castleman Disease Research Program.(Image: Courtesy of Penn Medicine) In pursuit of a cure, when ideas and options have run out A new book from Penn Medicine’s David Fajgenbaum chronicles his journey to beat Castleman disease, a rare disorder that he’s lived with for almost a decade.
Mounting brain organoid research reignites ethical debate Mounting brain organoid research reignites ethical debate Penn neuroscientists call for an ethical framework grounded in scientific principles for transplanting human “mini-brains” into animals as the field evolves.
A Q&A with Penn Medicine’s Jason Freedman for National Coming Out Day Jason Freedman (foreground) on his wedding day with husband, Neil, in 2016. (Image courtesy: Jason Freedman) Q&A A Q&A with Penn Medicine’s Jason Freedman for National Coming Out Day The assistant professor of clinical pediatrics discusses being out at Penn and shares some of his own experiences as a gay man.
How safe and effective are new pulmonary embolism devices? How safe and effective are new pulmonary embolism devices? A scientific statement from the American Heart Association, led by Penn Medicine, identifies the risks and benefits of new interventional devices compared to the use of blood thinners alone.
Gene therapy for Duchenne muscular dystrophy safely preserves muscle function Gene therapy for Duchenne muscular dystrophy safely preserves muscle function A Penn study shows delivering a “distant cousin” of a key protein prevented muscle damage without triggering an immune response in large animal models.
Penn alumnus Gregg L. Semenza awarded Nobel in Physiology or Medicine 2019 Gregg L. Semenza. Photo Courtesy of Johns Hopkins University. Penn alumnus Gregg L. Semenza awarded Nobel in Physiology or Medicine 2019 He is one of a trio of researchers sharing the award for their studies of how cells sense and adapt to varying oxygen levels.
Can the additive tree expand machine learning in medicine? nocred Can the additive tree expand machine learning in medicine? By combining elements of two widely used prediction models, the “additive tree” is a highly predictive model that is also easy to interpret.
Penn team creates first bile duct-on-a-chip Penn team creates first bile duct-on-a-chip The miniature, fabricated organ, replicating the structure and cellular makeup of the tissue, may lead to better understanding of the organ system and the differences between child and adult bile ducts.
As a nursing innovator, Therese Richmond thinks beyond hospital walls Andrea B. Laporte Professor of Nursing and Associate Dean for Research & Innovation. As a nursing innovator, Therese Richmond thinks beyond hospital walls During a four-decade career, Penn Nursing’s associate dean for research and innovation has tackled topics like gun violence by accounting for her patients’ environment in their long-term recovery.
A model for brain activity during brain stimulation therapy A model for brain activity during brain stimulation therapy Combined with data from other stimulation experiments , these models could help researchers determine the specific patterns of brain activity to target for improving memory.