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FDA approves personalized cellular therapy for advanced leukemia
hand holding bag containing manufactured CAR-T cells

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FDA approves personalized cellular therapy for advanced leukemia

Investigators at the Perelman School of Medicine and CHOP, who together led research, development, and clinical trials of the new therapy in collaboration with Novartis, hail the FDA’s approval as a game changer for the treatment of younger patients battling the aggressive blood cancer and a pivotal milestone in this new era of cellular therapies.

Penn Oral and Maxillofacial Surgeon Driven by Desire to ‘Make Someone Whole Again’

Penn Oral and Maxillofacial Surgeon Driven by Desire to ‘Make Someone Whole Again’

In his office at the University of Pennsylvania, oral and maxillofacial surgeon Rabie Shanti sits at his computer, clicking through photos of patients he’s operated on.He pulls up an image of a mouth open wide, tongue extended.

Katherine Unger Baillie

Successful Guide Dogs Have ‘Tough Love’ Moms, Penn Study Finds

Successful Guide Dogs Have ‘Tough Love’ Moms, Penn Study Finds

Much has been written of the pitfalls of being a helicopter parent, one who insulates children from adversity rather than encouraging their independence.

Michele W. Berger , Katherine Unger Baillie

In New Role at Penn, a GSE Alum and Formerly Homeless Teen, Finds a Way to Support Vulnerable Youth Across Pennsylvania

In New Role at Penn, a GSE Alum and Formerly Homeless Teen, Finds a Way to Support Vulnerable Youth Across Pennsylvania

Seth Morones-Ramírez, an alumnus of the University of Pennsylvania’s Graduate School of Education, grew up in and out of the foster-care system. At times, he was homeless: staying in a motel, car, group home or shelter or sleeping on the couches of kind-hearted friends.
Protons with a purpose
Protons with a Purpose, Roberts Proton Therapy

Protons offer a way to deliver radiation in a way that minimizes exposure to normal tissue. At the Roberts Proton Therapy Center, upwards of 5,000 people have received life-saving cancer care since the facility opened in 2010.

Protons with a purpose

As many as 115 patients treated each day. Upwards of 5,000 people who have received life-saving cancer care since 2010. As impressive as these numbers are, the outcomes at the Roberts Proton Therapy Center are even more so.

Christina Cook

Brain Training Has No Effect on Decision-making or Cognitive Function, Penn Researchers Report

Brain Training Has No Effect on Decision-making or Cognitive Function, Penn Researchers Report

During the last decade, commercial brain-training programs have risen in popularity, offering people the hope of improving their cognitive abilities through the routine performance of various “brain games” that tap cognitive functions such as memory, attention and cognitive flexibility.

Ali Sundermier , Queen Muse

Penn Researchers Engineer Macrophages to Engulf Cancer Cells in Solid Tumors

Penn Researchers Engineer Macrophages to Engulf Cancer Cells in Solid Tumors

One reason cancer is so difficult to treat is that it avoids detection by the body. Agents of the immune system are constantly checking the surfaces of cells for chemical signals that say they belong, but cancer cells express the same chemical signals as healthy ones. Without a way for the immune system to tell the difference, little stands in the way of cancer taking over.

Evan Lerner , Ali Sundermier

A Perturbed Skin Microbiome Can Be ‘Contagious’ and Promote Inflammation, Penn Study Finds

A Perturbed Skin Microbiome Can Be ‘Contagious’ and Promote Inflammation, Penn Study Finds

Even in healthy individuals, the skin plays host to a menagerie of bacteria, fungi and viruses. Growing scientific evidence suggests that this lively community, collectively known as the skin microbiome, serves an important role in healing, allergies, inflammatory responses and protection from infection.

Katherine Unger Baillie