Perelman School of Medicine

Penn Engineers Use Network Science to Predict How Ligaments Fail

When doctors diagnose a torn ligament, it’s usually because they can see ruptures in the ligament’s collagen fibers, visible on a variety of different scans. However, they also often treat patients with many of the symptoms of a tear, but whose ligaments don’t show this kind of damage.   

Evan Lerner

Improving Radiology’s Utility and Safety at Penn Dental Medicine

The oral cavity is a complex landscape, cavernous and full of irregular structures. Using a two-dimensional X-ray to map its variations can only reveal so much. That’s why a technological revolution that has made three-dimensional imaging of the teeth and jaws easier and safer has ushered in a transformation of practice in the dental clinic.

Katherine Unger Baillie

Penn Study Prompts Reevaluation of Assumptions on Role of Internal Clock in Human Disease

Abolishing the 24-hour clock by knocking out a key gene during development accelerates aging and shortens lifespan by two thirds in mice, but this effect is absent if the gene deletion is delayed until after birth, according to a new study published this week in Science Translational Medicine by scientists from the Perelman School of Medicine at the University of Pennsylvania.

Karen Kreeger

Penn Study Identifies Enzyme Key to Link Between Age-Related Inflammation and Cancer

For the first time, researchers have shown that an enzyme key to regulating gene expression -- and also an oncogene when mutated -- is critical for the expression of numerous inflammatory compounds that have been implicated in age-related increases in cancer and tissue degeneration, according to new research from the Perelman School of Medicine at the University of Pennsylvania. Inhibitors of the enzyme are being developed as a new anti-cancer target.

Karen Kreeger



In the News


Philadelphia Inquirer

Is there a chemical link to memory loss? Penn researchers get $11M to study dementia causes

The National Institutes of Health have awarded $11 million to Aimin Chen of the Perelman School of Medicine to study the link between chemical exposures and dementia.

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Philadelphia Inquirer

COVID patient who survived coma reunites with Penn care team

A COVID patient who survived his coma recently reunited with the Penn Medicine care team that helped save his life, including Jennifer Olenik of the Perelman School of Medicine.

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CNN

Vaping immediately affects vascular health and oxygen levels, study shows, even without nicotine

Research published by Marianne Nabbout while a resident at the Perelman School of Medicine finds that vaping has an immediate effect on blood vessels even if an e-cigarette doesn’t contain nicotine.

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Fox 29 (Philadelphia)

Former patient gives thanks to PA hospital staff after surviving coma, COVID-19 battle

A former COVID patient who spent six months in a coma returned to thank the Penn Medicine team that contributed to his survival, including Megan Carr-Lettieri.

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Forbes

Insomnia may be more common than you think. Here’s what to know

According to Penn Medicine, about 1 in 4 Americans experiences difficulty with sleep each year.

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