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Perelman School of Medicine
Penn Study Indicates that Gene Therapy Efficacy for LCA is Dynamic: Improvement is Followed by Decline in Vision
Gene therapy for Leber congenital amaurosis (LCA), an inherited disorder that causes loss of night- and day-vision starting in childhood, improved patients’ eyesight within weeks of treatment in a clinical trial of 15 children and adults at the Scheie Eye Institute at the Perelman School of Medicine at the University of Pennsylvania.
Off-Label Use of Device to Prevent Stroke in A-Fib Patients is Prevalent and Potentially Dangerous, According to Penn Medicine Study
The Lariat device, which has been cleared by the U.S. Food and Drug Administration (FDA) for soft tissue approximation (placement of a suture) during surgical procedures, is associated with a significant incidence of death and urgent cardiac surgery during its frequent off-label use to prevent stroke in patients with the irregular heartbeat known as atrial fibrillation.
Penn Medicine Researchers Receive $7.5 Million to Expand HIV Gene Therapy Work
Researchers from the Perelman School of Medicine and the Penn Center for AIDS Research (CFAR) have been awarded $7.5 million over five years from the National Institutes of Health to initiate a multi-project HIV study investigating a new gene therapy approach to render immune cells of HIV positive patients resistant to the virus.
NIH Awards $8 Million Renewal to Penn Medicine's Center of Excellence in Environmental Toxicology
The National Institutes of Environmental Health Sciences (NIEHS), part of the National Institutes of Health (NIH), has renewed its funding to the Center of Excellence in Environmental Toxicology (CEET), at the University of Pennsylvania’s Perelman School of Medicine, for the next five years.
Medical Education Risks Becoming Two-Tiered Unless Strong Research Focus is Preserved, Argue Philadelphia Medical Leaders
For more than 100 years, exposing students to basic and clinical research has been an essential component of a medical school education in the United States. However, today, new models of medical education in which research plays a minimal role are likely to create a two-tiered system of education, decrease the physician-scientist pipeline and diminish the application of scientific advances to patient care.
Penn Study Identifies Molecular Link Between DNA Damage and Premature Aging
Like a beloved pair of jeans, human DNA accumulates damage over time, and older people’s bodies can’t repair it as well. Many scientists believe a build up of damage can cause cells to enter an irreversible dormant state known as senescence.
Penn Pioneer in Personalized Medicine Advocates that National Translational Medicine Consortia is Best Equipped to Drive Human Phenotyping for the Clinic
President Barack Obama launched the "Precision Medicine Initiative” this past winter during the State of the Union address, and politicians on both sides of the aisle applauded the announcement. Broadly, precision medicine is meant to help diagnose individuals more accurately and better tailor treatment according to their physiology.
Penn Study Shows Computer-Assisted Diagnosis Tool Helps Physicians Assess Skin Conditions Without Aid from Dermatologists
In the first major study to examine the use of a computer-assisted, photo-driven differential diagnosis generator for skin conditions, researchers at the Perelman School of Medicine at the University of Pennsylvania found physicians routinely used the tool, without an increase in calling for inpatient dermato
Two Researchers from Penn's Perelman School of Medicine Elected to American Academy of Arts and Sciences
Two researchers from the Perelman School of Medicine at the University of Pennsylvania have been elected as new members to the American Academy of Arts and Sciences, one of the nation's most prestigious honorary societies and a leading center for independent policy research.
University of Pennsylvania Team Receive Prestigious National Clinical Research Award for HIV Breakthrough
Researchers from the Perelman School of Medicine at the University of Pennsylvania and the Penn Center for AIDS Research (CFAR) are among the 2015 recipients of the prestigious Clinical Research Achievement Award for their personalized gene therapy work in HIV.
In the News
Man does DNA test, not prepared for what comes back ‘unusually high’
César de la Fuente of the School of Engineering and Applied Science and Perelman School of Medicine says that Neanderthal DNA provides insights into human evolution, population dynamics, and genetic adaptations, including correlations with traits such as immunity and susceptibility to diseases.
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Rural jails turn to community health workers to help the newly released succeed
According to Aditi Vasan of the Leonard Davis Institute and Perelman School of Medicine, evidence is mounting in favor of the model of training community health workers to help their neighbors connect to government and health care services.
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What is food noise and how do you get rid of it?
According to Thomas Wadden of the Perelman School of Medicine, people taking GLP-1 drugs are finding that daily experiences that used to trigger a compulsion to eat or think about food no longer have that effect.
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How to die in good health
PIK Professor Ezekiel Emanuel says that incessantly preparing for old age mistakes a long life for a worthwhile one.
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Mayor Parker’s plan to ‘remove the presence of drug users’ from Kensington raises new questions
Shoshana Aronowitz of the School of Nursing and Ashish Thakrar of the Perelman School of Medicine comment on the lack of specificity in Philadelphia’s plan to remove drug users from Kensington and on the current state of drug treatment in the city.
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