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Perelman School of Medicine
Penn Medicine Research Reveals Suicides Are Far More Likely to Occur After Midnight
A new study by researchers at Penn Medicine is the first to reveal that suicides are far more likely to occur between midnight and 4 a.m. than during the daytime or evening. The research abstract was published recently in an online supplement of the journal Sleep and will be presented at SLEEP 2014, the 28th annual meeting of the Associated Professional Sleep Societies LLC.
Penn Study Highlights Significant Side Effects Experienced by BRCA Mutation Carriers Following Cancer Risk-Reducing Surgical Procedure
The majority of women with cancer causing BRCA1 and BRCA2 mutations experience sexual dysfunction, menopausal symptoms, cognitive and stress issues, and poor sleep following prophylactic removal of their Fallopian tubes and ovaries - a procedure known as risk-reducing salpingo-oophorectomy (RRSO) - according to results of a new study from the Abramson Canc
Quality Control: Penn Study Shows How Misfolded Proteins are Selected for Disposal
It’s almost axiomatic that misfolded proteins compromise how cells normally function and cause debilitating human disease, but how these proteins are detected and degraded within the body is not well understood.
Penn Study Shows Longest-lasting Cardiology Guidelines Built on Findings of Randomized Controlled Trials
Clinical practice guideline recommendations related to screening and treatment can change markedly over time as new evidence about best practices and clinical outcomes of various treatments emerges.
Penn Medicine: Sex-Specific Changes in Cerebral Blood Flow Begin at Puberty, Penn Study Finds
Puberty is the defining process of adolescent development, beginning a cascade of changes throughout the body, including the brain.
Penn Medicine's Innovation Grant Program Announces Second Round Winners
The Penn Medicine Center for Health Care Innovation will fund three new initiatives in the second round of its Innovation Grant Program. The program encourages Penn employees and students to submit their ideas for advancing health and health care delivery.
Penn Medicine: Clinical Trials Designed to Block Autophagy in Multiple Cancers Show Promise
In the largest group of results to date, researchers from Penn Medicine’s Abramson Cancer Center and other institutions have shown in clinical trials that the malaria drug hydroxychloroquine (HCQ) blocked autophagy in a host of aggressive cancers—glioblastoma, melanoma, lymphoma and myeloma, renal and colon cancers—and in some cases helped stabilize disea
Penn Team Identifies Promising New Target for Gum Disease Treatment
Nearly half of all adults in the United States suffer from the gum disease periodontitis, and 8.5 percent have a severe form that can raise the risk of heart disease, diabetes, arthritis and pregnancy complications.
"Bystander" Chronic Infections Thwart Development of Immune Cell Memory, Penn Study Finds
Studies of vaccine programs in the developing world have revealed that individuals with chronic infections such as malaria and hepatitis tend to be less likely to develop the fullest possible immunity benefits from vaccines for unrelated illnesses.
Penn Study Reveals Breastfeeding, Birth Control Pills May Reduce Ovarian Cancer Risk Among Women with BRCA Gene Mutations
Breastfeeding, tubal ligation – also known as having one’s “tubes tied” – and oral contraceptives may lower the risk of ovarian cancer for some women with BRCA gene mutations, according to a comprehensive analysis from a team at the University of Pennsylvania's Basser Research Center for BRCA and the
In the News
Fox 29 (Philadelphia)
Cannabis reclassification could be game-changer for U.S. drug policy
Michael Cirigliano of the Perelman School of Medicine says that marijuana deserves to be removed from the same category as LSD, heroin, and fentanyl.
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The Washington Post
Americans are sleeping more than ever. See how you compare
Mathias Basner of the Perelman School of Medicine says that work and traveling are the major sleep killers, with the majority of traveling being commuting to and from work.
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Newsweek
Man does DNA test, not prepared for what comes back ‘unusually high’
César de la Fuente of the School of Engineering and Applied Science and Perelman School of Medicine says that Neanderthal DNA provides insights into human evolution, population dynamics, and genetic adaptations, including correlations with traits such as immunity and susceptibility to diseases.
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Women’s Health
How does fat leave the body? Experts explain the weight loss process
Colleen Tewksbury of the School of Nursing and Perelman School of Medicine says that waist circumference is a more accessible and potentially more helpful measure for fat loss than stepping on a scale.
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Philadelphia Inquirer
Cardiac arrest recoveries are great stories, but they’re rare. We can fix that
In an opinion essay, Raina Merchant of the Perelman School of Medicine says that low survival rates for cardiac arrest can be improved by increasing rates of CPR.
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