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Sometimes a full-on assault isn't the best approach when dealing with a powerful enemy. A more effective approach, in the long run, may be to target the support system replenishing the supplies that keep your foe strong and ready for battle.
The kidney and liver cancer drug sorafenib holds metastatic thyroid cancer at bay for nearly twice as long as a placebo, according to a new study from researchers in the Abramson Cancer Center at the University of Pennsylvania published in the journal Lancet. This is the first effective treatment for thyroid cancer patients who progress following standard treatments.
Amita Sehgal, PhD, a professor of Neuroscience at the Perelman School of Medicine, University of Pennsylvania, describes in Cell a circuit in the brain of fruit flies that controls their daily, rhythmic behavior of rest and activity.
The sedative drugs diazepam (Valium) and lorazepam (Ativan) are equally effective in treating the prolonged seizures known as status epilepticus in children, according to a randomized, controlled study by a multi-institution team of researchers with the Pediatric Emergency Care Applied Research Network, including an expert from the Perelman S
Over the last few decades researchers have characterized a set of clock genes that drive daily rhythms of physiology and behavior in all types of species, from flies to humans. Over 15 mammalian clock proteins have been identified, but researchers surmise there are more.
Despite decades of common use for surgeries of all kinds, the precise mechanism through which general anesthesia works on the body remains a mystery. This may come as a surprise to the millions of Americans who receive inhaled general anesthesia each year.
When we get sick it feels natural to try to hasten our recovery by getting some extra shuteye. Researchers from the Perelman School of Medicine at the University of Pennsylvania found that this response has a definite purpose, in fruitflies: enhancing immune system response and recovery to infection.
Nonsteroidal antinflamatory drugs (NSAIDs) that block an enzyme called COX-2 relieve pain and inflammation but can cause heart attacks, stroke, heart failure, and even sudden cardiac death. This has prompted a decade-plus search for safer, but still effective, alternatives to these commonly prescribed, pain-relieving drugs.
WHO Tebelelo Secretse, ambassador of Botswana to the United States
Proton therapy is in the proverbial chicken or the egg scenario. Companies are pulling back on reimbursements to treat some cancers—notably prostate, breast and lung—because of the added expense and limited evidence to back it up.
Penn Medicine’s transfer command center gets patients from affiliated hospitals and hospitals outside Philadelphia to specialized care that can save lives, with comments from CEO Kevin Mahoney.
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Penn Medicine is phasing out the anesthesia desflurane at four of its six hospitals to eliminate harmful greenhouse gases, with remarks from Greg Evans.
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Casey Jo Humbyrd and Josh Baxter of the Perelman School of Medicine and colleagues will track data from running the Broad Street Run to understand how a healthy Achilles tendon functions.
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Bruce Brod of the Perelman School of Medicine says that prolonged or overuse of topical steroids can cause rosacea, skin thinning, stretch marks, and an extreme and debilitating withdrawal.
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Michael Cirigliano of the Perelman School of Medicine says that marijuana deserves to be removed from the same category as LSD, heroin, and fentanyl.
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