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Perelman School of Medicine
13 Novel Genetic Components of Coronary Artery Disease Identified
An international analysis of 14 genome-wide association studies involving over 100,000 patients has identified 13 new genetic risk factors for coronary artery disease (CAD).
New Findings on Drug Tolerance in Tuberculosis Suggest Ideas for Shorter Cures
New research on how tuberculosis (TB) bacteria develop multi-drug tolerance points to ways TB infections might be cured more quickly. The study was published online last week in Cell.
Penn Researchers Find New Role for Cancer Protein p53
PHILADELPHIA - The gene for the protein p53 is the most frequently mutated in human cancer. It encodes a tumor suppressor, and traditionally researchers have assumed that it acts primarily as a regulator of how genes are made into proteins.
Call for Medical Schools to Teach Students Health Policy Issues Facing Patients
PHILADELPHIA -- How would you like your car to be fixed by someone who had no knowledge of what it was like to drive?
Penn Researcher Receives $2 million From NIH to Test Macular Degeneration Drug
John Lambris, PhD, the Dr.
First International Collaboration on the Genetics of Alzheimer's Disease Is Launched
The launch of the International Genomics of Alzheimer’s Project (IGAP) – a collaboration formed to discover and map the genes that contribute to Alzheimer’s disease – was announced Feb. 1 by a multi-national group of researchers.
Immune Cells Protect Body from Invaders, According to Penn Researchers
PHILADELPHIA - So-called barrier sites -- the skin, gut, lung – limit the inner body’s exposure to allergens, pollutants, viruses, bacteria, and parasites. Understanding how the immune system works in these external surfaces has implications for understanding such inflammatory diseases as asthma, psoriasis, IBD, and food allergies, all of which occur at the body’s barriers.
Sideline Test Accurately Detects Athletes’ Concussions in Minutes, Penn Study Shows
PHILADELPHIA – A simple test performed at the sideline of sporting events can accurately detect concussions in athletes, according to study by researchers at the University of Pennsylvania School of Medicine. Current sideline tests can leave a wide amount a brain function untested following concussion.
New Study from Penn Medicine: Antidepressant Use Reduced Hot Flashes in Menopausal Women
“Our findings suggest that among healthy women who were not depressed or anxious, a 10 to 20 milligram dose of escitalopram – which is well below the dosage level for psychiatric use – provides a nonhormonal, off-label option that is effective and well-tolerated in the management of menopausal hot flashes,” said Elle
Researchers Uncover New Gene for Heart Failure in Caucasians
Nearly five million Americans live with heart failure, with as many as 700,000 new cases diagnosed each year. In addition to lifestyle factors, scientists have shown that heart failure has a strong heritable component, but identifying the responsible genes has been a major challenge.
In the News
Fox 29 (Philadelphia)
Cannabis reclassification could be game-changer for U.S. drug policy
Michael Cirigliano of the Perelman School of Medicine says that marijuana deserves to be removed from the same category as LSD, heroin, and fentanyl.
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The Washington Post
Americans are sleeping more than ever. See how you compare
Mathias Basner of the Perelman School of Medicine says that work and traveling are the major sleep killers, with the majority of traveling being commuting to and from work.
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Newsweek
Man does DNA test, not prepared for what comes back ‘unusually high’
César de la Fuente of the School of Engineering and Applied Science and Perelman School of Medicine says that Neanderthal DNA provides insights into human evolution, population dynamics, and genetic adaptations, including correlations with traits such as immunity and susceptibility to diseases.
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Philadelphia Inquirer
Cardiac arrest recoveries are great stories, but they’re rare. We can fix that
In an opinion essay, Raina Merchant of the Perelman School of Medicine says that low survival rates for cardiac arrest can be improved by increasing rates of CPR.
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Women’s Health
How does fat leave the body? Experts explain the weight loss process
Colleen Tewksbury of the School of Nursing and Perelman School of Medicine says that waist circumference is a more accessible and potentially more helpful measure for fat loss than stepping on a scale.
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