Perelman School of Medicine

Just released data from a clinical trial shows continued promise for a new minimally invasive treatment option for patients with severe aortic stenosis.  New research presented at the 2011 American College of Cardiology (ACC) Scientific Sessions from the first arm, Cohort A, of the Placement of Aortic Transcatheter Valves (PARTNER) Trial shows that transcatheter aortic valve implantation

Psoriasis is a common inflammatory skin disease, and if severe, has been demonstrated to be a risk factor for cardiovascular (CV) disease. However, the degree to which psoriasis is associated with major adverse cardiac events (MACE), such as heart attack, stroke, and cardiovascular death has not been defined.

Researchers at the University of Pennsylvania School of Medicine have determined that a well-known chemical process called acetylation has a previously unrecognized association with one of the biological processes associated with Alzheimer’s disease and related disorders.

By combining sophisticated mathematical techniques more commonly used by spies instead of scientists with the power and versatility of functional magnetic resonance imaging (fMRI), a Penn neurologist has developed a new approach for studying the inner workings of the brain.

A new analysis by researchers at the University of Pennsylvania School of Medicine of recent cardiology clinical practice guidelines has found that more than half of the experts involved in the development of these guidelines reported a conflict of interest (COI).

Researchers at the University of Pennsylvania’s Abramson Cancer Center have discovered a novel way of treating pancreatic cancer by activating the immune system to destroy the cancer’s scaffolding. The strategy was tested in a small cohort of patients with advanced pancreatic cancer, several of whose tumors shrank substantially.

For seniors, voting can be difficult: standing with a walker or cane in the voting booth, struggling to read the tiny print on the ballot or trying to punch the tiny button to vote for the intended candidate. Despite the desire to vote, the typical voting process leaves many seniors disenfranchised, particularly for residents of long term care facilities.

For rodent pups, bonding with mom isn’t hard-wired in the womb. It develops over the first few weeks of life, which is achieved by their maturing sense of smell, possibly allowing these mammals a survival advantage by learning to identify mother, siblings, and home.

The liver normally makes and stores fat, which is required in moderation for normal body function. However, if the process goes awry, excess fat in the liver can cause major liver damage.  In fact, fatty liver is a leading cause of liver failure in the United States, and is often brought on by obesity and diabetes.

When Medicare hospice eligibility criteria expand in 2011 as part of the Affordable Care Act of 2010, efforts to test whether palliative care and aggressive treatment provided concurrently will be judged based on costs.