Perelman School of Medicine

Katalin Kariko and Drew Weissman wearing lab coats.

Long-awaited accolades for mRNA scientists Katalin Karikó and Drew Weissman

Katalin Karikó and Drew Weissman’s key mRNA discoveries more than 15 years earlier made COVID vaccines possible. Now the global public has opportunities to honor them.

Doctor touches virtual image of kidneys and bladder.

How machine learning could aid compatibility in kidney transplantation

Through the PURM internship program, undergraduate students are further researching an algorithm developed to group kidney donor-recipient pairs into low-risk and high-risk groups for graft survival.

Desmond Patton stands with arms crossed in front of a window, which mirrors his image

Desmond Patton and the science of being human

Penn Integrates Knowledge University professor Desmond Upton Patton discusses his research in social media and violence, finding an interdisciplinary career in social work, communication, data science, and psychiatry, and why his open-mindedness never stops.

Microscopic rendering of mRNA gene editing.

‘In vivo’ RNA-based gene editing model for blood disorders developed

Researchers from Penn Medicine and The Children’s Hospital of Philadelphia show that gene editing tools can be delivered via lipid nanoparticles, which would reduce cost and increase access to cutting-edge gene therapies.

Microscopic rendering of tau proteins disintegrating microtubuli in a neuron axon.

Protein identified as a target for Alzheimer’s treatment

New Penn Medicine research finds that a tau-regulating protein suppresses deterioration, and suggests replenishing the protein may improve cognitive and motor function.

Could psychedelics simultaneously treat chronic pain and depression?

This summer, Ahmad Hammo, a rising third-year student in the School of Engineering and Applied Science, is conducting a pilot study to explore psilocybin’s potential as a therapy for chronic pain and the depression that often accompanies it.

Cesar de la Fuente at the BioPond in James Kaskey Memorial Park

Artificial intelligence is leveling up the fight against infectious diseases

In a new review, Presidential Assistant Professor Cesar de la Fuente and co-authors assess the progress, limitations, and promise of research in AI and infectious diseases.

A person walking with an elderly person.

Individuals with depression are more than two times as likely to be diagnosed with dementia

Penn Medicine research finds the risk of dementia is higher for men than women, and in individuals with multiple inpatient hospitalizations for depression.

Behavioral economics strategies can help patients quit smoking after a cancer diagnosis

Researchers from Penn Medicine and the Children’s Hospital of Philadelphia find ‘nudges’ from electronic health records could improve the implementation of tobacco use treatment.

Five Matriarca artisans at a table sharing a laptop.

Creating authentic connections in virtual teams

Working with Matriarca, an Argentinian sustainable goods distributor, scientists from the Wharton Neuroscience Initiative leveraged an exercise known as ‘Fast Friends’ to improve online collaboration within the organization.

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