Perelman School of Medicine

Illustration representing T cells attacking cancer cells

A new class of CAR T cells targets previously untargetable cancer drivers

Focusing on neuroblastoma, researchers from the Perelman School of Medicine and Children’s Hospital of Philadelphia have harnessed the immune system to destroy tumors.

Medical professional looking closely with a smartphone lens at pigment on a person’s arm.

Drugs designed for prostate cancer may treat melanoma in men

A new Penn study finds that testosterone contributes to sex differences in melanoma via the activation of the zinc transporter ZIP9.

Child wearing mask in school writes at a desk

With more kids eligible for vaccines, is the pandemic in a new phase?

With the FDA authorization last week, 28 million more children are eligible to be vaccinated against COVID-19. Experts from the School of Nursing and Perelman School of Medicine share their thoughts about what to expect in the weeks and months to come.

Historic move ushers in new era of care

Over eight hours, 310 patients moved to the Pavilion, a 17-story, 1.5-million-square-foot addition to the Hospital of the University of Pennsylvania campus.

Red blood cells play much larger role in immune system via DNA-binding

Penn Medicine researchers have uncovered mechanism of how red blood cells detect and bind DNA, opening a new area of research for treatment of inflammatory diseases.

Empty hospital bed and wheelchair in a health care facility with curtains drawn.

Yelp star ratings may reveal county-level death rate disparities

A one-star disparity on health care facility Yelp reviews could indicate a 60-death-per-year difference between some United States counties where those facilities are located.

diagray showing how a nanoparticle can respond to bacteria in the mouth and kill pathogens

‘Nanozyme’ therapy prevents harmful dental plaque buildup

An iron-oxide nanoparticle that is FDA-approved to treat anemia acts as an enzyme to activate hydrogen peroxide to suppress the growth of tooth-decay-causing biofilms in the human mouth, according to a study led by the School of Dental Medicine.

Hand of an African American person on a hospital bed with a hospital bracelet and an IV drip.

Racial disparities in avoidable hospitalizations for Medicare beneficiaries

A new Medical Care study by LDI Fellow Norma Coe and colleagues reveals racial disparities in avoidable hospitalizations that are even greater than in traditional Medicare.

Stock image of two vials of COVID-19 vaccines. One is upright, the other laying on its side. They both say "COVID-19 vaccine, LOT: D66A443, EXP: 03.22, INJECTION ONLY"

Four facts about the COVID-19 boosters

The FDA and CDC endorsed boosters of the Moderna and Johnson & Johnson COVID-19 vaccines just a month after the agencies did the same for a Pfizer/BioNTech booster. Here’s what’s known today about these shots.

A brain scan with highlighted genetic activity.

Genetic disease CDKL5 deficiency disorder could be treatable after childhood

The study finds that the CDKL5 gene, which plays an important role in proper brain development during childhood, is also active in adulthood, and that gene therapy may help adult patients.

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