Perelman School of Medicine

Drew Weisman and Katalin Kariko wear masks in a lab and look at liquid in a test tube.

Drew Weissman and Katalin Karikó receive 2021 Lasker Award

Weissman and Karikó’s mRNA technology is recognized for enabling rapid development of highly effective COVID-19 vaccines

Microscopic multicolor image of a colon.

Imaging technology maps cells tied to inflammatory bowel disease

“Imaging mass cytometry” shows how cells tied to inflammatory bowel disease affect intestinal tissue, generating new theories for the progression of Crohn’s disease and ulcerative colitis.

Doctor holding up an X-ray of a spine in front of a patient, seated.

How a diversity program enabled a childhood orthopaedics patient’s research dreams

The McKay Orthopaedic Research Lab’s Diversity, Equity, and Inclusion (DEI) committee’s conference grant program offers a welcoming environment and resources that support people of all identities, to engate in orthopaedic research.

Person in a white lab coat standing at a lab bench looking at a book. Scientific materials are on the table next to and above the person.

Test predicts which patients with rare blood disease will respond to treatment

A Penn Medicine study identifies blood proteins that indicate which patients with idiopathic multicentric Castleman disease are most likely to benefit from the only FDA approved treatment for the disease, and uncovers an alternative.

Gloved hand holding a SARS-CoV-2 antibody test.

At-home COVID-19 results with the click of a smartphone

Penn researchers have developed a highly-sensitive rapid antigen test that can detect small loads of SARS-CoV-2.

Person in full PPE administering a vaccine to another person sittting on a hospital bed.

mRNA COVID-19 vaccines induce T-cell responses in multiple sclerosis patients

Research from Penn Medicine shows mRNA COVID-19 vaccines are effective at inducing T-cell responses in multiple sclerosis patients who receive B cell-depleting Infusions even if their antibody responses are diminished.

Hands of person with muscular dystrophy holding a breathing apparatus.

Respiratory care program allows patients with neuromuscular disorders to thrive at home

Penn Medicine’s Jay and Randy Fishman Program for Home Assisted Ventilation has implemented dramatic advances in respiratory support and multidisciplinary care so patients can live safely at home.

microscopic rendering of three solid tumors being attacked by CAR T cells.

Engineering CAR T cells to activate a bodily response to solid tumors

A new Penn study shows that CAR T cells expressing RN7SL1, a naturally occurring RNA, can activate the body’s natural immune cells against difficult-to-treat cancers.

Deborah Culley standing by a railing at the Perelman School of Medicine in a white lab coat.

Deborah J. Culley on her vision for the future of Anesthesiology and Critical Care

Culley discusses her past research on the connection between anesthesia and post-operative cognitive dysfunction and her new role as chair of the Department of Anesthesiology and Critical Care.

A person in a mask holding a clipboard at the bottom of steps outside a home. On the porch are an unmasked adult and two unmasked children.

In hard-hit neighborhoods, Philly CEAL outreach aims to address COVID disparities

Through community engagement and improved information dissemination, researchers at Penn Nursing, Penn Medicine, and Annenberg, in conjunction with the City of Philadelphia, are working to increase vaccination and testing rates and decrease new COVID-19 infections.

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