Perelman School of Medicine

Penn-led consortium identifies more genetic markers for inherited testicular cancer

A new meta-analysis of nearly 200,000 men revealed 22 new genetic locations that could be susceptible to inherited testicular germ cell tumors—an increase of 40%.

Cross section of a hair follicle surrounded by cells.

Cytokine treatment promotes weight loss by ‘sweating’ fat

A seemingly unremarkable observation—greasy hair—showed Penn researchers how the immune system could be targeted to reverse obesity.

microscopic rendering of a virus cell next to a t cell.

Clarifying T cell ‘exhaustion’

T cells, which are among the most powerful weapons in the immune systems of humans and other vertebrates, remain substantially programmed to stay exhausted even many weeks after exposure to a virus ended.

New cell therapy shows potential against solid tumors with KRAS mutations

The new technology for cellular immunotherapy shows promising anti-tumor activity in the lab against hard-to-treat cancers driven the KRAS mutation.

Front entrance of the PHMC Public Health Campus on Cedar.

Penn Medicine’s new center to improve surgical equity for vulnerable patients

The Center for Surgical Health provides a new access point into sustainable, high-value surgical care for patients who typically rely on the emergency room for treatment.

Pregnant person in a mask having their pulse checked by a masked doctor.

Using race to diagnose anemia during pregnancy may increase its risk at delivery

Penn researchers suggest going against national guidelines and standardizing the threshold at which pregnant women are treated for anemia

100 years of insulin

On July 27, 1921, Canadian doctors Frederick Banting and Charles Best successfully isolated the hormone insulin, one of the most important breakthroughs in treating diabetes. Experts from around the University share their thoughts on the medical triumph on the 100th anniversary.

Person sitting with doctor who is showing them something on a tablet.

Spinal fluid biomarkers detect neurodegeneration, Alzheimer’s disease in living patients

Alzheimer’s disease and other forms of neurodegeneration can be identified using a combination of biomarkers in cerebrospinal fluid of living patients, Penn researchers find.

Row of three-story rowhouses in Philadelphia, some windows boarded up.

City-funded housing repairs in low-income neighborhoods impacts crime rates

Penn Medicine research suggests that investment in structurally damaged homes in low-income and minority neighborhoods are associated with reduced crime and improved public health.

Penn Medicine’s first living donor uterus transplant

Cheryl Cichonski-Urban donated her uterus to Chelsea Jovanovich through Penn Medicine’s Uterus Donation program. In May, Jovanovich gave birth to a baby boy.

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