School of Dental Medicine

Two from Penn named to new class of AAAS Fellows

Noted for their contributions to dental and biological sciences, respectively, Hyun (Michel) Koo of the School of Dental Medicine and Joshua Plotkin of the School of Arts and Sciences are part of the newest cohort of fellows of the American Association for the Advancement of Science.

Modeling the most common form of vision loss in older adults

Age-related macular degeneration is the leading cause of vision loss in people older than 50. Kathleen Boesze-Battaglia and colleagues have developed a model system that mimics many features of the human condition, giving scientists a platform to gain a deeper understanding of risk factors and possible treatments.

A diagram explains the action of the protein Del-1 and macrophages

To resolve inflammation, location matters

A single protein can both restrain the initiation of inflammation and help to actively resolve it, according to new research led by George Hajishengallis of the School of Dental Medicine. He and his colleague found that the type of cell that secretes the protein determines which activity the protein promotes.

group-sitting-on-stage-power-of-penn-backdrop

The Power of Penn in London

In London, President Amy Gutmann presented the vision for the University’s $4.1 billion campaign, The Power of Penn.

5 tips to scare away cavities

Beyond the inevitable sugar high, what are the implications of consuming a glut of candy? Pediatric dentist Maria Velasco suggests coming up with a plan, then giving away the rest of the treats.

Drivers of inflammation provide valuable targets for new gum disease therapies

A subset of T cells contributes to the inflammation and bone loss that characterizes periodontitis, a severe form of gum disease. According to new research by George Hajishengallis and scientists at the National Institutes of Health, drugs that specifically inhibit these cells may offer an effective therapy.

Targeting a viral vulnerability to treat disease

Robert Ricciardi company ViRAZE utilizes interdisciplinary approaches to drug discovery. Its first target is molluscum contagiosum, a disease that targets children and immune-compromised adults with no current FDA-approved therapy.

Regrowing dental tissue with stem cells from baby teeth

In a clinical trial led by Songtao Shi of the School of Dental Medicine, stem cells extracted from baby teeth were used to regrow the living tissue in teeth damaged by injury. The promising findings highlight the potential of dental stem cells, which could be used in a wide range of dental procedures, or treating certain systemic diseases.

Mentoring program introduces high school students to dentistry

The Summer Mentorship Program introduces first-generation and under-represented high school students in Philadelphia to higher education possibilities, including Penn Dental School's four-week immersion program that includes hands-on experience and mentorship with current dental students.

Dental plaque is no match for catalytic nanoparticles

A recent study found that nanoparticles can break down dental plaque with nanoparticles that target biofilms, preventing tooth decay in humans and animal models without damaging surrounding oral tissue.

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