School of Veterinary Medicine

Dramatic calorie restriction, diets reduced by 40 percent of a normal calorie total, have long been known to extend health span, the duration of disease-free aging, in animal studies, and even to extend life span in most animal species examined.

As part of a breast-cancer diagnosis, doctors analyze the tumor to determine which therapies might best attack the malignancy. But for patients whose cancer is triple-negative — that is, lacking receptors for estrogen, progesterone and Her2 — the options for treatment dwindle. Triple-negative cancers, or TNBC, also tend to be more aggressive than other cancer subtypes.

According to the Guinness World Records, the longest any person has held a continuous vocal note is just shy of two minutes. That’s quite an achievement.Compared to the Pacific midshipman fish, however, the endurance of the human vocal cord is no match. Midshipman fish can generate a mating call that emits continuously from their bodies for a full hour.

Gene therapy holds promise for treating a variety of diseases, including some inherited blinding conditions. But for a gene therapy to be effective, one must know the precise gene responsible for a given individual’s disorder and develop a tailored treatment.

In a historic move, the U.S. Food and Drug Administration (FDA) today approved a gene therapy initially developed by researchers at the University of Pennsylvania and Children’s Hospital of Philadelphia (CHOP) for the treatment of a rare, inherited form of retinal blindness.

Four members of the University of Pennsylvania faculty have been named Fellows of the American Association for the Advancement of Science. Election as an AAAS Fellow is an honor bestowed upon members of AAAS, the world’s largest general scientific society, by their peers.

A new study by University of Pennsylvania veterinary researchers has found that blood samples collected from an intravenous catheter using a special “mixing” technique are as accurate as those collected via venipuncture, in which a needle is used to access the vein directly.

By Erica AndersenCertain mosquitoes don’t get heartworm, and Barbara Biney was keen to find out why.

Cancer of the pancreas is rare, but deadly. Research from Penn Vet may slow its spread.

Cancer of the pancreas is a deadly disease, with a median survival time of less than six months. Only one in 20 people with pancreatic cancer survives five years past the diagnosis. The reason is the cancer’s insidiousness; tumor cells hide deep inside the body, betraying no symptoms until late in the disease, when the cancer has almost invariably spread to other organs.