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John Gearhart, Stem Cell Pioneer, Named Penn's Institute for Regenerative Medicine Director and PIK Professor

    • John Gearhart, Stem Cell Pioneer, Named Penn's Institute for Regenerative Medicine Director and PIK Professor

    PHILADELPHIA –- John Gearhart, who led a research team that first identified and isolated human embryonic stem cells, has been named director of the Institute for Regenerative Medicine at the University of Pennsylvania and also a Penn Integrates Knowledge Professor.

    Jordan Reese

    Penn Researchers Identify First Sex Chromosome Gene Involved in Meiosis and Male Infertility

    • Penn Researchers Identify First Sex Chromosome Gene Involved in Meiosis and Male Infertility

    PHILADELPHIA -– A team of scientists led by University of Pennsylvania veterinary researchers have identified a gene, TEX11, located on the X chromosome, which when disrupted in mice renders the males sterile and reduces female fecundity. This is the first study of the genetic causes of infertility that links a particular sex chromosome meiosis-specific gene to sterility.

    Jordan Reese

    Agent Orange Chemical, Dioxin, Attacks the Mitochondria To Cause Cancer, Says Penn Research Team

    • Agent Orange Chemical, Dioxin, Attacks the Mitochondria To Cause Cancer, Says Penn Research Team

    PHILADELPHIA— Researchers with the University of Pennsylvania School of Veterinary Medicine have demonstrated the process by which the cancer-causing chemical dioxin attacks the cellular machinery, disrupts normal cellular function and ultimately promotes tumor progression.

    Jordan Reese

    Penn Researchers Shine the Light of Venus to Learn How the Herpes Virus Invades Cells

    • Penn Researchers Shine the Light of Venus to Learn How the Herpes Virus Invades Cells

    PHILADELPHIA -– University of Pennsylvania researchers have uncovered an important step in how herpes simplex virus, HSV-1, uses cooperating proteins found on its outer coat to gain entry into healthy cells and infect them. Further,the study’s authors say, they have demonstrated the effectiveness of monitoring these protein interactions using biomolecular complementation.

    Jordan Reese