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For Penn synthetic biologist César de la Fuente and his team, these concepts aren’t some far-off ideal. They’re projects already in progress, and they have huge real-world implications should they succeed.
Through his research, Yoichiro Mori, the Calabi-Simons Visiting Professor of Mathematics and Biology, demonstrates how mathematical theories can provide insights into complex, living systems.
A Penn study reveals the epigenetic pathway that controls social behavior in carpenter ants, finding that the ants reprogram up to five days after they hatch, while reprogramming was ineffective at the 10-day mark.
What drives the biology behind alcohol cravings has remained largely unknown. A new Penn study shows how a byproduct of the alcohol breakdown produced mostly in the liver travels to the brain’s learning system and impacts behavior around environmental cues to drink.
To confront the ills of the opioid epidemic, scientists must develop a fundamental understanding of the biology of pain. Biologist Ishmail Abdus-Saboor’s work is setting the stage for screening alternative drugs and uncovering new pathways that an opioid-alternative could target.
Tissue gets stiffer when it’s compressed. That stiffening response is a long-standing biomedical paradox, as common sense dictates that when you push the ends of a string together, it loosens tension, rather than increasing it. New research explains the mechanical interplay between that fiber network and the cells it contains.
In just five generations, an altered microbiome can lead to genome-wide evolution in fruit flies, according to new research led by Paul Schmidt and postdoc Seth Rudman of the School of Arts and Sciences.
Scientists have studied the nematode worm Caenorhabditis elegans for decades, making essential contributions to basic science. In the latest milestone, a team uses cutting-edge technology to individually profile the genes expressed in more than 80,000 cells in a developing C. elegans embryo.
Concern over fake news and online trolls is widespread and warranted, but researchers have identified another impediment to the free flow of information in social networks. The phenomenon, which they term “information gerrymandering,” arises from the structure of a social network and introduces bias into collective decisions.
Biologists Erol Akçay and Marco Smolla used mathematical models to show that societies that favor generalists, who have a wide range of skills, are less well-connected than those societies that favor specialists, who are highly skilled at a smaller number of traits.
According to Colleen Tewksbury of the School of Nursing, research suggests that L-theanine may help support stress management, sleep, and potentially weight management.
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Scott Hensley of the Perelman School of Medicine is working on a flu vaccine to provide protection against 20 subtypes of flu that may pose a pandemic threat in the future.
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A study by César de la Fuente of the Perelman School of Medicine and colleagues used AI to recreate molecules from ancient humans that could be potential candidates for antimicrobial treatments.
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A study by Christoph Thaiss and Maayan Levy of the Perelman School of Medicine and colleagues finds that long COVID’s neurological symptoms, like brain fog, memory loss, and fatigue, may stem from serotonin reduction.
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A study by Christoph Thaiss and Maayan Levy of the Perelman School of Medicine and colleagues suggests that serotonin could be a target for long COVID treatment.
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A study by Christoph Thaiss and Maayan Levy of the Perelman School of Medicine and colleagues suggests that several current hypotheses for the pathophysiology of long COVID are linked by a single pathway that is connected by serotonin reduction.
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