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Biology
To improve dunes, plant more beach grass
Pairing biology and cinema studies, Bianca Charbonneau and Yoni Gottlieb have produced a light-hearted, informative video that teaches the proper method for planting dune grasses to build a healthier dune ecosystem.
Immune cells involved in triple-negative breast cancer could offer future therapeutic target
New research led by Rumela Chakrabarti reveals how immune cells called myeloid-derived immunosuppressor cells contribute to the progression of triple-negative breast cancer, a particularly aggressive cancer. Pairing chemotherapy with a drug that blocks these cells may one day help stem its growth.
A study in prenatal gene editing with DNA in utero
A Penn Medicine and CHOP team shows the first example of using base-editing tools to treat a disease in animal models in utero.
Making fossils move to build better robots
Aja Carter, a Ph.D. candidate in paleontology, builds robots based on fossilized animals that crawled out of the sea about 300 million years ago. She’s pioneering a new field that she calls paleo-bio-inspired robotics.
Seven Penn researchers receive NIH Director Awards
Seven researchers from the Perelman School of Medicine, School of Veterinary Medicine, and School of Engineering and Applied Science are to receive National Institutes of Health Director Awards, highly competitive grants to support innovative biomedical research.
Learn from the experts with the Penn Science and Lightbulb Cafes
The lecture series, hosted by the School of Arts and Sciences, offers a casual setting in which researchers can present their work and engage with the attendees during a Q&A period, giving a glimpse into the research at Penn.
New center will study the complex genomics within individual cells
Junhyong Kim and James Eberwine are leading a multi-disciplinary team in developing cutting-edge technologies that can assess the genetic material inside individual compartments of single cells. The new Center for Sub-Cellular Genomics aims to revolutionize therapies for diseases such as bipolar disorder, autism, and Alzheimer’s disease.
Cancer cells send out ‘drones’ to battle the immune system from afar
Checkpoint inhibitor therapies have made metastatic melanoma and other cancers a survivable condition, but only for some patients. Researchers uncovered a novel mechanism by which tumors suppress the immune system, raising the possibility that a straightforward blood test could predict which patients could respond to immunotherapy.
Understanding the social dynamics that cause cooperation to thrive, or fail
Many examples of cooperation exist in nature, but it’s far from a universal characteristic of human or animal groups. Using a mathematical model, Erol Akçay showed that less randomly connected social networks make cooperation more likely, but those dynamics may ultimately lead to cooperation’s collapse.
Frigid polar oceans, not coral reefs, are hot spots for formations of fish species
Tropical waters contain a dazzling diversity of fish species compared to colder ocean areas. Yet a new study paradoxically indicates that the colder waters are home to the highest species formation rates.
In the News
Bird flu virus has been spreading in U.S. cows for months, RNA reveals
Louise Moncla of the Veterinary School of Medicine says that the bird flu virus is clearly being transmitted to cows in some way.
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Man does DNA test, not prepared for what comes back ‘unusually high’
César de la Fuente of the School of Engineering and Applied Science and Perelman School of Medicine says that Neanderthal DNA provides insights into human evolution, population dynamics, and genetic adaptations, including correlations with traits such as immunity and susceptibility to diseases.
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When is the best time to take L-theanine—morning or night?
According to Colleen Tewksbury of the School of Nursing, research suggests that L-theanine may help support stress management, sleep, and potentially weight management.
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Is the flu shot market a slam dunk for mRNA vaccines? Experts aren’t so sure
Scott Hensley of the Perelman School of Medicine is working on a flu vaccine to provide protection against 20 subtypes of flu that may pose a pandemic threat in the future.
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Thanks, Neanderthals: How our ancient relatives could help find new antibiotics
A study by César de la Fuente of the Perelman School of Medicine and colleagues used AI to recreate molecules from ancient humans that could be potential candidates for antimicrobial treatments.
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Long COVID brain fog may originate in a surprising place, say scientists
A study by Christoph Thaiss and Maayan Levy of the Perelman School of Medicine and colleagues finds that long COVID’s neurological symptoms, like brain fog, memory loss, and fatigue, may stem from serotonin reduction.
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