Skip to Content Skip to Content

Genetics

An unsolved mystery: Why are we sleepy when sick?
Researcher peering through microscope.

David Raizen, left, and PURM student Hina Sako working in the Raizen Lab.

nocred

An unsolved mystery: Why are we sleepy when sick?

David Raizen, a professor of neurology, alongside PURM student Hina Sako, spent the summer moving forward research examining how sickness affects sleep.
Genetic switch turns tumor suppressor into oncogene in colorectal cancer
Fluorescent microscopy of colon cancer cells..

(Image: Yuhua Tian)

Genetic switch turns tumor suppressor into oncogene in colorectal cancer

Researchers from the School of Veterinary Medicine have shown that an enzyme that suppresses early-stage colorectal cancer switches to become an oncogene as the cancer progresses.

Liana F. Wait

These eight diseases are so rare that drug firms haven’t tried treating them with gene therapy. A $97 million program aims to help

These eight diseases are so rare that drug firms haven’t tried treating them with gene therapy. A $97 million program aims to help

Gene therapy for a rare form of blindness will be tested at Penn Medicine while gene therapy for a condition that causes skeletal deformities and seizures will be tested at the Children’s Hospital of Philadelphia.

‘In vivo’ RNA-based gene editing model for blood disorders developed
Microscopic rendering of mRNA gene editing.

Image: iStock/Ozgu Arslan

‘In vivo’ RNA-based gene editing model for blood disorders developed

Researchers from Penn Medicine and The Children’s Hospital of Philadelphia show that gene editing tools can be delivered via lipid nanoparticles, which would reduce cost and increase access to cutting-edge gene therapies.

Alex Gardner

Katalin Susztak hunts for a cure for kidney disease
Katalin Susztak

Katalin Susztak, professor of internal medicine, nephrology, and genetics at the Perelman School of Medicine.

(Image: Penn Medicine News)

Katalin Susztak hunts for a cure for kidney disease

Throughout her career, the professor of internal medicine, nephrology, and genetics has had a profound impact on the way kidney disease is identified, prevented, and managed.

From Penn Medicine News