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Internal Medicine
Novel model for studying intestinal parasite could advance vaccine development
The intestinal parasite Cryptosporidium causes frequent outbreaks in the U.S., and has been historically difficult to study. A novel model of infection from Penn Vet serves as a new tool to pursue a vaccine.
How to quell a cytokine storm
An international team finds new ways to dampen an overactive immune system, and can influence new drug targets for lupus and other autoimmune disorders.
We’re only as good as our microbiomes are happy
Understanding the microbiome, the collection of bacteria, viruses, and fungi in the gut, is helping to sort out the intricacies of diet, chronobiology, cancer treatment, and more.
Certain strains of bacteria associated with diabetic wounds that do not heal
A new study finds that whether a wound like a diabetic foot ulcer heals or progresses to a worse outcome, including infection or even amputation, may depend on the microbiome within that wound.
App predicts risk of developing hernia following abdominal surgery
A Penn-developed app can predict the likelihood that a patient will develop an incisional hernia following abdominal surgery, utilizing electronic health records to identify the most common risk factors for patients.
A DIY colorectal cancer screening kit
At-home screening kits are found to be effective, with roughly a quarter of patients overdue for screenings mailing the completed kits back within two months.
Hep C-infected organs may be viable option for patients awaiting a heart transplant
Successfully treating the virus post-transplant has the potential for expanding the use of HCV-infected organs, including hearts, to broaden the donor pool for those on a transplant waitlist.
What’s overlooked can be fatal
New research shows that spontaneous coronary artery dissection is not only far more common than was previously thought, but that patients may benefit most from conservative treatment that allows the body to heal on its own.
Immune profiling: A new opportunity for drug development
Immunologists, oncologists, and infectious disease specialists are thinking about the immune system in a new way based on its integral and ubiquitous ties to human health, amassing data on its role in gastroenterology, neurology, cardiovascular disease, and metabolic disease.
To resolve inflammation, location matters
A single protein can both restrain the initiation of inflammation and help to actively resolve it, according to new research led by George Hajishengallis of the School of Dental Medicine. He and his colleague found that the type of cell that secretes the protein determines which activity the protein promotes.
In the News
Shoppers react after 10 million pounds of meat recalled due to listeria contamination
Michael Cirigliano of the Perelman School of Medicine says that people who ate recalled chicken within the last day should be watched to ensure they aren’t developing fever, diarrhea, or nausea.
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Patients are relying on Lyft, Uber to travel far distances to medical care
According to Krisda Chaiyachati of the Perelman School of Medicine, some insurance companies and cancer treatment centers pay for ride-hailing services to reduce missed medical appointments.
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Fox 29 anchor Mike Jerrick diagnosed with prostate cancer, recovering from surgery
Michael Cirigliano of the Perelman School of Medicine made the initial diagnosis of prostate cancer for veteran newscaster Mike Jerrick.
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Philadelphia heat: Tips to avoid heat-related illness as dangerous heat lingers
Michael Cirigliano of the Perelman School of Medicine says that heat stroke, which can be fatal, starts as heat exhaustion then leads to more symptoms as the temperature rises.
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What competitive eating does to the body
David Metz of the Perelman School of Medicine explains some of the effects of speed-eating.
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As a primary care physician, here’s how I hope to partner with AI
In an opinion essay, Jeffrey Millstein of the Perelman School of Medicine says that patients and clinicians should be active participants when incorporating AI into primary care.
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