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Since the first paper describing a brain organoid—a miniature, simplified version of a human organ—published in 2013, many new technologies, from organs-on-a-chip to organoids, have continued biomedical science down the innovative path.
Seven researchers from the Perelman School of Medicine, School of Veterinary Medicine, and School of Engineering and Applied Science are to receive National Institutes of Health Director Awards, highly competitive grants to support innovative biomedical research.
Robert Ricciardi company ViRAZE utilizes interdisciplinary approaches to drug discovery. Its first target is molluscum contagiosum, a disease that targets children and immune-compromised adults with no current FDA-approved therapy.
In a clinical trial led by Songtao Shi of the School of Dental Medicine, stem cells extracted from baby teeth were used to regrow the living tissue in teeth damaged by injury. The promising findings highlight the potential of dental stem cells, which could be used in a wide range of dental procedures, or treating certain systemic diseases.
Twenty patients at Penn Medicine have been cured of the hepatitis C virus following lifesaving kidney transplants from deceased donors who were infected with the disease. The kidney transplants for these patients, too, are functioning just as well as kidneys that are transplanted from similar donors without HCV.
A new drug-delivery technology which uses red blood cells to shuttle nano-scale drug carriers, called RBC-hitchhiking, has been found to dramatically increase the concentration of drugs ferried precisely to selected organs.
The One Health Communications Group is a collaboration that brings together several schools and centers to develop groundbreaking health research in a cross-disciplinary and innovative environment.
Dramatic calorie restriction, diets reduced by 40 percent of a normal calorie total, have long been known to extend health span, the duration of disease-free aging, in animal studies, and even to extend life span in most animal species examined.
Shoshana Aronowitz of the School of Nursing and Ashish Thakrar of the Perelman School of Medicine comment on the lack of specificity in Philadelphia’s plan to remove drug users from Kensington and on the current state of drug treatment in the city.
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Michael Cirigliano of the Perelman School of Medicine says that monkeypox spreads mostly through skin-to-skin contact, though the risk of exposure in normal settings is low.
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A longtime Philadelphia schoolteacher has completed his final donation of blood at Penn’s Perelman Center for Advanced Medicine, with remarks from Kristin G. Christensen and Donald Siegel of the Perelman School of Medicine.
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Paolo Silvestrini of the School of Veterinary Medicine says that the most frequent reasons for abrupt, sudden canine sneezing may involve a foreign body or allergic reactions to environmental allergens.
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David Vaughn of the Perelman School of Medicine says a delay in diagnosis of testicular cancer of more than six months is an independent predictor of a lower chance of survival.
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Mitchell Lazar of the Perelman School of Medicine says distribution of fat plays a major role in determining how deleterious added weight is.
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