10.21
Internal medicine
Failure of mitochondrial quality control causes heart disease
Failure of mitochondrial quality control causes heart disease
A new Penn Medicine study reveals a well-known protein participates in mitophagy; mutations in the genes of that protein suppress mitophagy and cause disease.
The price of noise
The price of noise
Silence is a rare commodity these days, because society has only gotten louder. “And we're all paying a price for it in terms of our health,” says Mathias Basner, an associate professor of sleep and chronobiology in psychiatry at Penn.
How safe and effective are new pulmonary embolism devices?
How safe and effective are new pulmonary embolism devices?
A scientific statement from the American Heart Association, led by Penn Medicine, identifies the risks and benefits of new interventional devices compared to the use of blood thinners alone.
Penn team creates first bile duct-on-a-chip
Penn team creates first bile duct-on-a-chip
The miniature, fabricated organ, replicating the structure and cellular makeup of the tissue, may lead to better understanding of the organ system and the differences between child and adult bile ducts.
Reproductive science by experts, for teens
Reproductive science by experts, for teens
High school girls who take part in the Penn Academy for Reproductive Science get a hands-on lab course with top epigenetic and reproductive health experts.
The diet-microbiome connection in inflammatory bowel disease
The diet-microbiome connection in inflammatory bowel disease
Dogs with a Crohn’s-like disease fed a special diet were found to have characteristic changes in their gut microbiomes, paralleling changes seen in children with Crohn’s.
Hormone that helps stabilize blood pressure cuts blood transfusions by half
Hormone that helps stabilize blood pressure cuts blood transfusions by half
A Penn study shows that trauma patients with severe blood loss, most often gunshot victims, need only half the usual volume of blood when receiving an arginine vasopressin treatment.
Many kidneys discarded in the United States would be transplanted in France
Many kidneys discarded in the United States would be transplanted in France
A new study, led by Penn Medicine and Paris Transplant Group, found French transplant centers are far more likely to transplant kidneys from older donors.
Nicotine-free e-cigarettes can damage blood vessels
Nicotine-free e-cigarettes can damage blood vessels
A single e-cigarette can be harmful to the body’s blood vessels—even when the vapor is entirely nicotine-free, according to a new study by researchers in the Perelman School of Medicine at the University of Pennsylvania.
Lung cell transplant boosts healing after the flu
Lung cell transplant boosts healing after the flu
A serious case of the flu can cause lasting damage to the lungs. In a study in mice, researchers found that transplanting cells from the lungs of healthy animals enhanced healing in others that had had a severe respiratory infection.
In the News
Philadelphia Inquirer
E-Cigarettes Disappoint in a Workplace Quit-Smoking Study
The Perelman School of Medicine’s Scott Halpern led a study on the effects of vaping on smoking cessation. Halpern found that e-cigarettes were no more helpful than other stop-smoking tools, and that “the very best way to help them quit is to offer them money.”
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WHYY (Philadelphia)
New Blood Test for Pregnant Women Could Predict Preterm Birth
The Perelman School of Medicine’s Michal Elovitz discussed the results from her research exploring methods for predicting preterm births. The study’s results were published in Science.
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