9.30
Internal Medicine
A New York Times medical mystery and a determined sister saved this patient’s life
A New York Times medical mystery and a determined sister saved this patient’s life
A patient in New York with an acute case of bronchitis was in respiratory distress. When family members read a similar account in the New York Times, they tracked down the specialist cited in the article—Maxim Itkin at the Perelman School of Medicine.
Hepatitis C-infected kidneys get a green light for further transplant research
Hepatitis C-infected kidneys get a green light for further transplant research
Results from a multicenter study point to expanding the donor kidney supply, and alleviating long transplant wait times, with hep-C infected organs, then treating the disease post-transplant.
Gender parity in heart failure research calls for more women authors and patients
Gender parity in heart failure research calls for more women authors and patients
An analysis led by Penn Medicine identifies gender disparities in authorship of heart failure guideline citations and clinical trials.
The perfect balancing act of inflammation rests on a single molecule
The perfect balancing act of inflammation rests on a single molecule
A new Penn study reveals a molecular mechanism that helps the body mount balanced responses to deadly infections.
How our body’s internal clocks communicate may impact our overall health
How our body’s internal clocks communicate may impact our overall health
Most cells contain molecular clocks, but the requirement of peripheral clocks for rhythmicity, and their effects on physiology, are not well understood. Now, a new study reveal the roles of the hepatocyte clock in cell communication and metabolism.
The gut shields the liver from fructose-induced damage
The gut shields the liver from fructose-induced damage
A new study shows how excessive consumption of fructose, whether via food or beverage, overwhelms gut defenses and results in the development of fatty liver.
To heal meniscus injuries, researchers go to the heart of a cell
To heal meniscus injuries, researchers go to the heart of a cell
Using an enzyme inhibitor in meniscus cells, a Penn team is able to soften the cells’ nucleus and promote access to previously impassible tissue.
Researchers identify novel genetic variants linked to Type 2 diabetes
Researchers identify novel genetic variants linked to Type 2 diabetes
Largest-ever study of its kind finds variants that may predispose some people to develop the disease and related conditions like coronary heart disease and chronic kidney disease.
Stimulating immune cleanup crew offers affordable possibility for treating rare genetic disorder
Stimulating immune cleanup crew offers affordable possibility for treating rare genetic disorder
Compounds that mimicked the process known as efferocytosis alleviated signs of leukocyte adhesion deficiency type-1 in an animal model, according to work led by the School of Dental Medicine’s George Hajishengallis
Researchers discover a key mechanism of cytokine storm in Castleman Disease
Researchers discover a key mechanism of cytokine storm in Castleman Disease
The discovery by Penn researchers may be applicable to COVID-19 patients, as some experience the same hyper-response of the immune system.
In the News
The New York Times
Organ transplants dive amid virus crisis, start to inch back
Peter Reese of the Perelman School of Medicine spoke about the resumption of organ transplants. “Transplant centers and patients really want to get going again, but there are all these questions,” he said. “We need to be finding places that maintained their transplant rates and finding out what they did.”
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The New York Times
Can melatonin vapes safely help people sleep?
Julio Chirinos of the Perelman School of Medicine wrote an editorial to accompany a new study about the effects of marathon running on the heart. “Exercise is great for the entire body, including the arteries,” he said.
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U.S. News & World Report
What is syphilis, and why are rates rising?
Amy Forrestel of the Perelman School of Medicine spoke about the symptoms, spread, and long-term effects of syphilis. If left untreated, the sexually transmitted infection “can wreak a lot of havoc” on the body, said Forrestel.
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Associated Press
Study: Safe to transplant hepatitis C-infected hearts, lungs
Peter Reese of the Perelman School of Medicine commented on a recent study about the safety and efficacy of pairing hepatitis C-infected organ transplants with fast, preventative treatments to block recipients from contracting the infection. The combination may work “because maybe the virus hasn’t had the chance to establish itself,” said Reese.
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Men’s Health
Why gene editing may hold the promise of a herpes cure
Sita Awasthi of the Perelman School of Medicine discussed the challenges researchers face in pursuing a cure for herpes. In spite of advances in CRISPR technology, Awasthi emphasizes the continued need for a preventive vaccine.
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Reader’s Digest
8 surprising heartburn causes you need to take seriously
Kristle Lynch of the Perelman School of Medicine described the causes, symptoms, and consequences of heartburn.
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