Skip to Content Skip to Content

Medicine

Reset All Filters
1644 Results
Busting myths about the Asian American ‘model minority’
Patient with a face mask looking at a computer with a medical professional.

Busting myths about the Asian American ‘model minority’

Two new studies highlight the problem with aggregating diverse groups of people into a single category of “Asian American” when applied to cardiovascular disease and cancer diagnosis and outcomes.

From Penn LDI

A new method to increase effectiveness of nanomedicines
Microscopic view of nanomedicine particles attacked by immune system proteins.

Upon injection into the blood, nanomedicines (blue spheres) are immediately attacked by proteins of the immune system called complement proteins (orange). Complement proteins cause rapid destruction of the nanomedicine, and also induce an anaphylaxis-like reaction. By attaching complement-degrading proteins (yellow ninjas made of protein) to the surface of nanomedicines, Penn researchers have largely solved this problem, potentially allowing more diseases to be safely treated by nanomedicine.(Image: Penn Medicine News)

A new method to increase effectiveness of nanomedicines

Penn Medicine researchers have developed a new technique that uses complement inhibitor Factor I to prevent proteins from attacking treatment-carrying nanoparticles so they can better reach targets within the body.

Sophie Kluthe

Researchers find new potential targets for skin-cancer treatment
Microscopic view of skin tissue cells.

Researchers find new potential targets for skin-cancer treatment

Making up for the genetic mutations of MLL4 in skin cells, one of the most commonly mutated genes across all of human cancers, may keep epithelial cancer from beginning and progressing

Alex Gardner

A structural blueprint of nanoparticles to target acute lung inflammation
X-ray of lungs illuminated in red.

A structural blueprint of nanoparticles to target acute lung inflammation

Targeting neutrophils, a type of white blood cell that, when overactive, contributes to acute lung inflammation, is a potential new route to diagnose and treat acute respiratory distress syndrome.

From Penn Medicine News

From foundational discoveries to profound impact
weissman and kariko in the lab Today, Weissman and colleagues are working to develop a pan-coronavirus vaccine capable of protecting the population against SARS, MERS, SARS-CoV-2, and more. At BioNTech, Karikó is overseeing parallel but distinct research on a range of diseases in which patients receive mRNA encoding therapeutic proteins. (Image: Peggy Peterson)

From foundational discoveries to profound impact

How decades of mRNA research at Penn made powerful new COVID-19 vaccines possible—and opened a new vista for future discoveries.

Ashley Rabinovitch