Medicine

Penn Vet’s Wildlife Futures seek to unravel the mystery of the disappearing barn owl

New research from Penn Medicine finds that activation of natural killer cells is linked to longer survival, and suppressive immune cells is tied to poor response.

The Clayco Foundation award to Penn Medicine will go toward safety trials of a new small molecule drug aimed at treating RVCL, a rare, fatal disease with no cure.

The original structure of the nation’s first chartered hospital—home to early mental health and maternity care—is a living symbol of innovation.

Researchers at Penn Medicine have created a generalizable strategy to identify new targets for CAR T cell therapy.

A long-term follow-up from one of the earliest CAR T cell therapy clinical trials shows potential cures in more than one-third of patients treated at Penn Medicine.

Researchers at Penn Engineering developed an ‘asthma-on-a-chip’ system that mimics the mechanical stresses experienced by human airways during an asthma attack. The innovation enables scientists to probe how unhealthy lung tissue responds to compression in ways previously impossible to observe directly in patients.

A Penn Medicine-created vaccine platform swaps out lipid nanoparticles with a different kind of nanoparticle to simplify manufacturing, making the vaccines easier and more cost-effective to produce, transport, store, and distribute.

Researchers at the Perelman School of Medicine have uncovered a new understanding of retinal cell development which may help pave the way for future retina transplants, and could restore sight to people whose conditions currently have no effective treatments.

Two new Penn Medicine studies show that microtubules help determine how the heart changes shape under stress, and a common signaling pathway acts as a key controller of where the building materials for these cells’ growth are delivered inside them; the findings point to possible new ways to address causes of heart failure.