Medicine | Penn Today

Immune protein a possible target to slow Parkinson’s disease

Researchers at Penn Medicine have found that blocking a key neuronal protein interrupts the spread of toxins to healthy neurons in preclinical studies.

1 min. read

Gloved hand holding a scan of four brains

Most who meet proposed CTE criteria do not show disease signs at autopsy

New research from Penn Medicine finds proposed traumatic encephalopathy syndrome criteria often don’t match CTE pathology at autopsy, raising concerns about misdiagnosis and potential mental health impacts for at-risk groups.

2 min. read

Penn research into Friedreich’s ataxia reveals how DNA folding can silence a key gene

A new Penn Medicine study uncovers how a balance between gene activity and DNA folding determines where genes sit in the nucleus—and how misplacement contributes to the neurodegenerative and cardiac disorder.

Specialized RNA molecules could counter ALS neurodegeneration

Researchers at Penn Medicine have discovered short RNA chaperones that bind to the primary target of ALS, restore its function, and protect motor neurons in a preclinical model, pointing toward a new RNA-based therapeutic strategy.

2 min. read

Bringing hope to uterine health patients

Physician-scientist Kate O’Neill directs innovative research that helps people suffering from infertility, endometriosis, and other issues build families and have excellent quality-of-life.

1 min. read

From left to right: Justin Wang, Janine Haros, and Eric Lee in a clinical room at the Scheie Eye Institute, holding documents and smiling together

Empowering unhoused patients through comprehensive eye care

Penn fourth-years Eric Lee, Janine Haros, and Justin Wang will use a President’s Engagement Prize to elevate vision health in unhoused individuals across Philadelphia through free eye screenings, tailored care coordination, and interactive patient education.

4 min. read

Using AI to help predict cardiac arrests

A Penn Engineering and Penn Medicine team built CAMEL, an artificial intelligence model that forecasts dangerous cardiac rhythms before they strike. Their findings pave the way for a new era of real-time, predictive heart care.

2 min. read

Stopping and restarting certain GLP-1s to lose weight may make the drug less effective

A preclinical study from Penn Medicine reveals that people seeking weight loss from GLP-1s may need to consistently take the medication long term.

African American person tearing off an I Voted Today sticker

Voting is linked to living longer

A new study co-authored by SP2’s Femida Handy shows that voting is associated with reduced mortality risk in older adults.

2 min. read

Cross section rendering of human kidneys

Blood test predicts kidney failure risk to Black Americans years before onset

A new study from Penn Medicine identifies disease risk among those carrying the high-risk APOL1 gene variant before kidney function declines.

2 min. read

Filters

Immune protein a possible target to slow Parkinson’s disease

Most who meet proposed CTE criteria do not show disease signs at autopsy

Penn research into Friedreich’s ataxia reveals how DNA folding can silence a key gene

Specialized RNA molecules could counter ALS neurodegeneration

Bringing hope to uterine health patients

Empowering unhoused patients through comprehensive eye care

Using AI to help predict cardiac arrests

Stopping and restarting certain GLP-1s to lose weight may make the drug less effective

Voting is linked to living longer

Blood test predicts kidney failure risk to Black Americans years before onset