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New CAR T treatment opens doors for kidney patients
Anatomy of two kidneys

Image: jitendrajadhav via Getty Images

New CAR T treatment opens doors for kidney patients

An early Penn Medicine trial demonstrates CAR T cells can safely desensitize even the most challenging transplant candidates.

Matt Toal

2 min. read

GLP-1 use linked to lower breast cancer incidence in large cohort study
A person holding a GLP-1 applicator.

Image: Iuliia Burmistrova via Getty Images

GLP-1 use linked to lower breast cancer incidence in large cohort study

A retrospective analysis of more than 110,000 women between the ages of 45 and 80 found that those who take GLP-1 medications are about 30% less likely to develop breast cancer than those who do not take GLP-1 medications.

2 min. read

A Philly man didn’t know if he’d ever get off the kidney transplant waiting list. CAR T made it happen

A Philly man didn’t know if he’d ever get off the kidney transplant waiting list. CAR T made it happen

“Since its first use in a 2010 clinical trial involving leukemia patients at Penn, efforts to broaden CAR-T’s applications have advanced slowly. The therapy has not proven effective against solid cancers, although some studies have shown potential.”

To deliver hospital-level care at home, practice makes perfect
Nurses practice how to talk to patients about properly storing medications

Nurses practice how to talk to patients about properly storing medications while they are enrolled in Hospital at Home.

(Image: Courtesy of Penn Medicine News)

To deliver hospital-level care at home, practice makes perfect

Years of planning come to fruition as Penn Medicine’s Hospital at Home teams test run a new era of patient care devoted to better outcomes and fewer readmissions.

From Penn Medicine News

2 min. read

An AI tool to speed antibiotic discovery
Jacob R. Gardner, César de la Fuente and Marcelo Torres, holding a 3D-printed example of the kind of antibiotic peptide they generated

(From left) Co-authors Jacob R. Gardner, César de la Fuente and Marcelo Torres, holding a 3D-printed example of the kind of antibiotic peptide they generated using AI.

(Image: Sylvia Zhang)

An AI tool to speed antibiotic discovery

APEX is an AI model that predicts whether or not a given peptide is likely to have antimicrobial properties. Now, APEXGo can identify antibiotic candidates with laboratory activity against disease-causing bacteria, simply by searching large datasets.

Ian Scheffler

2 min. read

 A home away from home for transplant patients and families
Penn’s Transplant House outdoor entrance.

Image: Courtesy of Penn Medicine

 A home away from home for transplant patients and families

Penn’s Clyde F. Barker Penn Transplant House offers a comforting and affordable refuge for transplant patients and families—with community and hope.

Matt Toal

2 min. read

Major gaps in online info for patients about AI and cancer

Major gaps in online info for patients about AI and cancer

In a new Penn Medicine study, researchers screened web pages to understand how patients are using AI in their searches in an effort to work with the emerging technology to offer more accessible, high-quality resources.

From clinic to classroom: How two physicians are rethinking healthcare through business
Samuel Nathan, a doctor from Ghana, and Dan Menéndez, a U.K.-trained physician

Samuel Nathan (left) and Dan Menéndez, students in the Wharton MBA and Lauder Institute MA in International Studies joint-degree program

(Image: Courtesy of The Lauder Institute)

From clinic to classroom: How two physicians are rethinking healthcare through business

The Wharton MBA and Lauder Institute MA in International Studies joint-degree program emphasizes regional expertise, culture, and policy so its students can learn to develop health care solutions.

From the Lauder Institute

2 min. read

A different way of thinking about side effects
A person holding a prescription pill bottle in their hand.

Image: Catherine McQueen via Getty Images

A different way of thinking about side effects

The new book “Side Effects: The Social Ecology of Adverse Drug Reactions,” by sociologist Jason Schnittker and former Ph.D. student Duy Do, makes the case that side effects are a product of social, cultural, and institutional forces.

3 min. read