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Pediatrics

Children, the pandemic, and long-term mental health consequences
Young person sitting at a table, leaning chin on crossed arms, wearing a mask. There are books, colored pencils, an abacus, a notepad and more scattered around.

Children, the pandemic, and long-term mental health consequences

New work from Penn Nursing and the Children’s Hospital of Philadelphia describes the importance of recognizing COVID-19’s psychological effects on young people and the pivotal role pediatric nurses in all settings can play.

Michele W. Berger

Pregnant mothers’ antibodies to SARS-CoV-2 transfer to their fetuses
Pregnant person sits on a seat on public transit wearing a face mask.

Pregnant mothers’ antibodies to SARS-CoV-2 transfer to their fetuses

Antibodies to coronavirus in pregnant women cross the placenta efficiently, and are found at similar concentrations in their newborns, according to a large study from researchers at the Perelman School of Medicine.

Melissa Moody

Racial disparities in pediatric diabetes treatment
Adolescent child holding a teddy bear having their blood pressure taken by a nurse.

Racial disparities in pediatric diabetes treatment

Despite similar outpatient appointment attendance rates, significant disparities in continuous glucose monitoring and insulin pump use were observed in non-Hispanic Black children over 20 years.

From Penn Nursing News

Progress toward a treatment for Krabbe disease
Sequence of 8 MRI images showing treated versus untreated brains from 16 to 52 weeks

Treating dogs with Krabbe disease, a rare and fatal condition that also affects infants, with a gene therapy targeted to the brain led to remarkable results in a study led by a team from the School of Veterinary Medicine. (Image: Courtesy of Charles Vite)

Progress toward a treatment for Krabbe disease

The inherited disease, which typically kills children before their second birthday, has no cure, but a School of Veterinary Medicine study in a canine model offers hope for an effective gene therapy with lasting results.

Katherine Unger Baillie

Getting gene therapy to the brain
Illustration of brain with DNA double helix

Crossing the blood-brain barrier to treat the whole brain has been a challenge for researchers aiming to treat inherited neurodegenerative disease. The results from a study in a large animal model offer “a big advance” in this pursuit, says John Wolfe of Penn Vet, Penn Medicine, and CHOP.

Getting gene therapy to the brain

Using a large animal model of genetic brain disease, researchers led by John H. Wolfe of the School of Veterinary Medicine, Perelman School of Medicine, and Children’s Hospital of Philadelphia delivered an effective treatment across the blood-brain barrier to correct the whole brain.

Katherine Unger Baillie

Two studies highlight proton therapy for pediatric brain cancer
A clinic worker stands at the gantry of the Roberts Proton Therapy center machine.

Two studies highlight proton therapy for pediatric brain cancer

A pair of new studies done at Penn and the Children’s Hospital of Philadelphia add to the growing body of research showing the potential benefits of proton therapy.

Penn Today Staff

How much time should kids really be spending on screens?
three toddlers on a mat on the floor of a playroom looking at a tablet

How much time should kids really be spending on screens?

Screens, tablets, and mobile devices are everywhere, and parents have to navigate exposure for their children in a digital world, balanced with physical activities and sleep.

Penn Today Staff

The NICU ensures safe sleep one swaddle at a time
person holding swaddled newborn baby

The NICU ensures safe sleep one swaddle at a time

The Women & Babies Hospital Neonatal Intensive Care Unit focuses on promoting sleep safety techniques with parents while their baby is still in the NICU.

Penn Today Staff

Improvements needed for care, safety of pediatric patients in hospital settings
Woman in blue shirt sitting with desk behind her. Desk is filled with lamp, two computer screens, a printer and a coffee mug tree.

Eileen Lake is the Jessie M. Scott Endowed Term Chair in Nursing and Health Policy, a professor of nursing and sociology, and associate director of Center for Health Outcomes and Policy Research at the School of Nursing at the University of Pennsylvania.

Improvements needed for care, safety of pediatric patients in hospital settings

Penn Nursing’s Center for Health Outcomes and Policy Research found that when acute-care settings have better work environments for nurses, children are better protected.