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How sex differences may influence lung injury
Lung cells with RNA labeled in pink in each cell

AT2 cells, a type of lung cell that produces surfactant and give rise to gas-exchanging cells, can be infected by SARS-CoV-2. Research by Penn Vet scientists showed that differences in gene expression between male and female AT2 cells may help explain why older males have more severe outcomes from COVID-19 and similar diseases. (Image: Courtesy of the Anguera laboratory)

How sex differences may influence lung injury

Comparing lung cells from male and female mice, School of Veterinary Medicine scientists found gene expression differences that may explain why older males are at a higher risk than females for worse outcomes from COVID-19 and similar diseases.

Katherine Unger Baillie