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A subset of T cells contributes to the inflammation and bone loss that characterizes periodontitis, a severe form of gum disease. According to new research by George Hajishengallis and scientists at the National Institutes of Health, drugs that specifically inhibit these cells may offer an effective therapy.
Gene therapies have had success in treating blindness but can’t save areas of the retina where cells have already died. In a new effort, School of Veterinary Medicine scientists John Wolfe and William Beltran will attempt to develop a stem-cell-based approach that restores vision.
Susan M. Domchek, Daniel E. Polsky, Marie Celeste Simon, and Rachel M. Werner are four of the 85 newly-elected members of the National Academy of Medicine.
Melanie Kornides of the School of Nursing, Jennifer Lewey of the Perelman School of Medicine, and C. Alix Timko of Medicine and the Children’s Hospital of Philadelphia are pursuing research that examines the role of sex and gender on health, supported by the Building Interdisciplinary Research Careers in Women’s Health program.
The language people use in these social media posts can make these predictions as accurately as the tools clinicians use in medical settings to screen for the disease.
A new study shows patients with treatable mutations identified by liquid biopsies rather than tissue biopsies also largely respond to therapy.
Robert H. Vonderheide, the Abramson Cancer Center director, talks innovation, discoveries, FDA approvals, and how to deliver top-of-the-line cancer care.
New research led by Rumela Chakrabarti reveals how immune cells called myeloid-derived immunosuppressor cells contribute to the progression of triple-negative breast cancer, a particularly aggressive cancer. Pairing chemotherapy with a drug that blocks these cells may one day help stem its growth.
A Penn Medicine and CHOP team shows the first example of using base-editing tools to treat a disease in animal models in utero.
Sleep paralysis has been linked to the supernatural for centuries. Neuroscientists work to uncover the science of REM disorders.
Michael Cirigliano of the Perelman School of Medicine says that marijuana deserves to be removed from the same category as LSD, heroin, and fentanyl.
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Marion Leary of the School of Nursing is co-leading a national coalition seeking to convince federal agencies to recognize the field of nursing as a STEM profession.
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Mathias Basner of the Perelman School of Medicine says that work and traveling are the major sleep killers, with the majority of traveling being commuting to and from work.
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Dean Mark Wolff of the School of Dental Medicine says there aren’t enough robust, large-scale clinical studies or trials demonstrating the supposed benefits of oil pulling.
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Cynthia Otto of the School of Veterinary Medicine says that fentanyl can be absorbed across the mucous membranes in canine noses, causing dogs to face a life-threatening overdose.
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