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2005 Results
Structure of Key Molecule in Immune System Provides Clues for Designing Drugs, According to Penn Study

Structure of Key Molecule in Immune System Provides Clues for Designing Drugs, According to Penn Study

PHILADELPHIA - A team from the University of Pennsylvania School of Medicine and Utrecht University has deciphered a key step in an evolutionarily old branch of the immune response. This system, called complement, comprises a network of proteins that “complement” the work of antibodies in destroying foreign invaders.

Karen Kreeger

Penn Researchers Identify Potential Target for Breast Cancer Therapy

Penn Researchers Identify Potential Target for Breast Cancer Therapy

PHILADELPHIA – Overexpression or hyperactivation of ErbB cell-surface receptors drives the growth of many breast cancers. Drugs, like Herceptin, that block the receptors’ signals halt tumor progression in some patients. However, not all patients’ tumors respond, with some becoming resistant over time.

Karen Kreeger

Penn Medicine Establishes Hand Transplant Program

Penn Medicine Establishes Hand Transplant Program

PHILADELPHIA - The Penn Transplant Institute, the Department of Orthopaedic Surgery and the Division of Plastic Surgery at the Hospital of the University of Pennsylvania (HUP) have collaborated to form the Penn Hand Transplant Program.

Olivia Fermano

Weightlifting Slashes Lymphedema Risk After Breast Cancer Treatment

Weightlifting Slashes Lymphedema Risk After Breast Cancer Treatment

(SAN ANTONIO) -- Weightlifting may play a key role in a program to prevent the painful limb-swelling condition lymphedema following breast cancer treatment, according to new research from the University of Pennsylvania School of Medicine.

Holly Auer

Color-Changing “Blast Badge” Detects Exposure to Explosive Shock Waves

Color-Changing “Blast Badge” Detects Exposure to Explosive Shock Waves

PHILADELPHIA - Mimicking the reflective iridescence of a butterfly's wing, investigators at the University of Pennsylvania School of Medicine and School of Engineering and Applied Sciences have developed a color-changing patch that could be worn on soldiers' helmets and uniforms t

Karen Kreeger

Process Leading to Protein Diversity in Cells Important for Proper Neuron Firing

Process Leading to Protein Diversity in Cells Important for Proper Neuron Firing

PHILADELPHIA – Cells have their own version of the cut-and-paste editing function called splicing. Researchers at the University of Pennsylvania School of Medicine have documented a novel form of splicing in the cytoplasm of a nerve cell, which dictates a special form of a potassium channel protein in the outer membrane.

Karen Kreeger