Health Sciences

PHILADELPHIA -– A team of scientists led by University of Pennsylvania veterinary researchers have identified a gene, TEX11, located on the X chromosome, which when disrupted in mice renders the males sterile and reduces female fecundity. This is the first study of the genetic causes of infertility that links a particular sex chromosome meiosis-specific gene to sterility.

PHILADELPHIA -– Scientists at the University of Pennsylvania School of Veterinary Medicine have identified a protein, ISG15, that inhibits the Ebola virus from budding, the process by which viruses escape from cells and spread to infect neighboring cells.

PHILADELPHIA –- Students at West Philadelphia’s Sayre High School who are taking a health-education class have been working with University of Pennsylvania nurse practitioner students and Penn School of Nursing faculty to learn accurate growth and diabetes-risk-factor assessment.

PHILADELPHIA -– Sarah Tishkoff, a leading global expert in human genetics, has been named the sixth Penn Integrates Knowledge University Professor at the University of Pennsylvania.The announcement was made today by Penn President Amy Gutmann and Provost Ronald Daniels.

PHILADELPHIA— Researchers with the University of Pennsylvania School of Veterinary Medicine have demonstrated the process by which the cancer-causing chemical dioxin attacks the cellular machinery, disrupts normal cellular function and ultimately promotes tumor progression.

PHILADELPHIA -– University of Pennsylvania researchers have uncovered an important step in how herpes simplex virus, HSV-1, uses cooperating proteins found on its outer coat to gain entry into healthy cells and infect them. Further,the study’s authors say, they have demonstrated the effectiveness of monitoring these protein interactions using biomolecular complementation.

PHILADELPHIA -– Researchers from the University of Pennsylvania and Johns Hopkins University have uncovered another reason why one of the most commonly activated proteins in cancer is so dangerous. As reported in Nature Genetics this week, the Myc protein can stop the production of at least 13 microRNAs, small pieces of nucleic acid that help control which genes are turned on and off.

PHILADELPHIA -– A team of researchers from the University of Pennsylvania School of Veterinary Medicine has identified the protein interactions involved in the immune system process that fights infection yet, in certain inflammatory diseases, runs amok and attacks friendly tissue.

PHILADELPHIA -- The University of Pennsylvania is launching the Institute for Regenerative Medicine, a new cross-disciplinary endeavor to investigate and harness the therapeutic potential of stem cells in the treatment of cancer, diabetes, cardiovascular disease, degenerative diseases, wound healing and aging. Two renowned Penn scientists, Jonathan A. Epstein and Ralph L.

PHILADELPHIA - Three faculty members of the University of Pennsylvania have been named Fellows of the American Association for the Advancement of Science (AAAS).