Health Sciences

Rescuing Fruit Flies from Alzheimer’s Disease

Investigators have found that fruit fly (Drosophila melanogaster) males -- in which the activity of an Alzheimer’s disease protein is reduced by 50 percent -- show impairments in learning and memory as they age.

Karen Kreeger

Jumping Genes Provide Extensive “Raw Material” for Evolution, Penn Study Finds

PHILADELPHIA - Using high-throughput sequencing to map the locations of a common type of jumping gene within a person’s entire genome, researchers at the University of Pennsylvania School of Medicine found extensive variation in these locations among the individuals they studied, further underscoring the role of these errant genes in maintaining genetic

Karen Kreeger

Penn-Led Collaboration Mimics Library of Bio-Membranes for Use In Nanomedicine, Drug Delivery

PHILADELPHIA –- An international collaboration led by chemists and engineers from the University of Pennsylvania has prepared a library of synthetic biomaterials that mimic cellular membranes and that show promise in targeted delivery of cancer drugs, gene therapy, proteins, imaging and diagnostic agents and cosmetics safely to the body in the emerging field called nanomedicine.  

Jordan Reese



In the News


The New York Times

Can melatonin vapes safely help people sleep?

Julio Chirinos of the Perelman School of Medicine wrote an editorial to accompany a new study about the effects of marathon running on the heart. “Exercise is great for the entire body, including the arteries,” he said.

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Rolling Stone

Can melatonin vapes safely help people sleep?

Philip Gehrman of the Perelman School of Medicine commented on the use of melatonin to aid sleep. “There have been quite a few randomized trials showing that melatonin is no better than placebo to help people sleep,” he said.

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“Academic Minute” (WAMC, Northeast Public Radio)

Jonathan Moreno on bioethics and the transformation of health care in America

PIK Professor Jonathan Moreno discussed the book “Everybody Wants to Go to Heaven but Nobody Wants to Die: Bioethics and the Transformation of Health Care in America,” which he co-authored with President Amy Gutmann.

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The New York Times

The F.D.A. is in trouble. Here’s how to fix it

Steven Joffe of the Perelman School of Medicine spoke about the tensions between groups that want medical products to be proven effective before the F.D.A. approves them for public use and groups that believe patients can make their own decisions once the products pass basic safety testing. “The F.D.A. has been moving in the latter direction under great political and public pressure,” he said.

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The New York Times

These patients are hard to treat

Mary Naylor of the School of Nursing spoke about her work leading an effort to reduce hospitalizations among Medicare patients using “hot spotting,” a model that allocates extra resources to “super-utilizers,” people who need more health care services than the average individual.

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