Health Sciences

Penn Medicine: Evidence of Alzheimer's in Patients with Lewy Body Disease Tracks with Course of Dementia

Patients who had a diagnosis of Parkinson’s disease (PD) with dementia (PDD) or dementia with Lewy bodies (DLB) and had higher levels  of Alzheimer’s disease (AD) pathology in their donated post-mortem brains also had more severe symptoms of these Lewy body diseases (LBD) during their lives, compared to those whose brains had less AD pathology, according to research from the 

Karen Kreeger

Linking Human Genome Sequences to Health Data Will Change Clinical Medicine, says Penn Expert

The value of intersecting the sequencing of individuals’ exomes (all expressed genes) or full genomes to find rare genetic variants -- on a large scale -- with their detailed electronic health record (EHR) information has “myriad benefits, including the illumination of basic human biology, the early identification of preventable and treatable illnesses, and the identification and validation of

Karen Kreeger

Penn: Epigenetic Change Ties Mitochondrial Dysfunction to Tumor Progression

Mitochondria, the mighty energy factories of the cell, often malfunction in cancer, as well as in other conditions such as aging, neurodegenerative disease and heart disease. Whether these changes in mitochondria actually contribute to the spread of cancer, however, has been controversial.

Katherine Unger Baillie

Penn’s quest to battle Alzheimer’s

John Trojanowski and Virginia Man-Yee Lee of the Perelman School of Medicine have been conducting Alzheimer’s research for more than 30 years, and have made three major discoveries—all of which have become strong foundations for those working on Alzheimer’s disease and related disorders around the world.

Lauren Hertzler



In the News


6ABC.com

Bird flu suspected in deaths of 200 snow geese in Pennsylvania’s Lehigh Valley

Stephen Cole of the School of Veterinary Medicine says that indoor cats are contracting bird flu through raw pet foods of poultry origin or raw milk products.

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NPR

Tuberculosis rates plunge when families living in poverty get a monthly cash payout

Aaron Richterman of the Perelman School of Medicine says that there are large and underappreciated benefits of cash-transfer programs, such as potentially ending a tuberculosis epidemic.

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Self

The surgeon general calls for new warning labels on alcohol—here’s the truth about how it impacts your health

Henry Kranzler of the Perelman School of Medicine says that alcohol’s effects on the brain are observed more readily because it’s the organ of behavior.

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Newsweek

Cancer breakthrough as ‘speckles’ may reveal best treatment

A paper co-authored by PIK Professor Shelley Berger finds that patterns of “speckles” in the heart of tumor cells could help predict how patients with a common form of kidney cancer will respond to treatment options.

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Time

Scientists are racing to develop a new bird flu vaccine

Drew Weissman and Scott Hensley of the Perelman School of Medicine are testing a vaccine to prevent a strain of H5N1 bird flu in chickens and cattle.

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