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Health Sciences
A Bash Between Friends
It wasn’t long ago that Maria Soltero-Rivera learned an important lesson: “Different is good.” “We’ve been working so hard doing this, and this little girl puts into a few simple words exactly what we’ve been trying to communicate to everyone,” Soltero-Rivera says. “You just learn so much from these kids.”
Penn Study Finds Link between Physician Training and Brand Name Prescribing
Physicians in training are twice as likely to order a costly brand-name statin (used to lower blood cholesterol levels) when supervised by senior physicians who prefer those medications in their own practice, according to a new study led by researchers at the
Researchers at Penn Develop Scar-like Culture Systems to Understand and Treat Fibrosis
A scar might be a reminder of an accident or surgery, but the fibrous tissue that makes up a scar also forms after a heart attack and arises in solid tumors as well as in chronic diseases such as liver cirrhosis and muscular dystrophy. Implanted medical devices and materials are similarly surrounded by fibrous capsules that impede their function.
Penn Vet Team Shows a Protein Modification Determines Enzyme’s Fate
The human genome encodes roughly 20,000 genes, only a few thousand more than fruit flies. The complexity of the human body, therefore, comes from far more than just the sequence of nucleotides that comprise our DNA, it arises from modifications that occur at the level of gene, RNA and protein.
Vision-Restoring Gene Therapy Also Strengthens Visual Processing Pathways in Brain, According to Penn Study
Since 2007, clinical trials using gene therapy have resulted in often-dramatic sight restoration for dozens of children and adults who were otherwise doomed to blindness. Now, researchers from the Perelman School of Medicine at the University of Pennsylvania and The Children’s Hospital of Philadelphia (CHOP), have found evidence that this sight restoration leads to strengthening of visual pathways in the brain, published this week in Science Translational Medicine.
Hydraulic Fracturing Linked to Increases in Hospitalization Rates in the Marcellus Shale Region, According to Penn Study
Hospitalizations for heart conditions, neurological illness, and other conditions were higher among people who live near unconventional gas and oil drilling (hydraulic fracturing), according to new research from the University of Pennsylvania and Columbia University published this week in PLOS ONE.
Fruitfly Sperm Cells Reveal Intricate Coordination in Stem Cell Replication, Penn Study Finds
Stem cells are key for the continual renewal of tissues in our bodies. As such, manipulating stem cells also holds much promise for biomedicine if their regenerative capacity can be harnessed. However, understanding how stem cells govern normal tissue renewal is a field still in its infancy.
Elective Surgery Is Associated with Lower Risk of Death than Drugs for Ulcerative Colitis Treatment, Penn Study Finds
Patients over 50 with ulcerative colitis (UC), a chronic disease of the colon, who undergo surgery to treat their condition live longer than those who are treated with medications, according to a new study from the Perelman School of Medicine at the University of Pennsylvania.
Imagination Institute at Penn Awards Nearly $3M to Develop ‘Imagination Quotient’
The Imagination Institute, based at the University of Pennsylvania’s Positive Psychology Center, has announced nearly $3 million worth of grants to researchers at 16 institutions. The grants are aimed at the development of better ways of assessing and promoting imagination and creativity.
Disrupting Cells’ ‘Powerhouses’ Can Lead to Tumor Growth, Penn Study Finds
Cancer cells defy the rules by which normal cells abide. They can divide without cease, invade distant tissues and consume glucose at abnormal rates.
In the News
Sugar-coated gold nanoparticles could replace some antibiotics
According to a Penn Medicine study, a new therapy involving laser light and sugar-coated gold nanoparticles can reduce tooth decay and infected wounds without needing antibiotics.
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A new strategy to attack aggressive brain cancer shrank tumors in two early tests
A clinical trial led by Stephen Bagley of the Perelman School of Medicine suggests that targeting two associated proteins with CAR T cell therapy could be a viable strategy for shrinking brain tumors.
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Alzheimer’s may be caused by a build-up of fat in brain cells
A study by Michael Haney of the Perelman School of Medicine suggests that the root cause of Alzheimer’s is a build-up of fat droplets in brain cells.
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Cats aren’t jerks. They’re just misunderstood
James Serpell of the School of Veterinary Medicine says that the domestic cat suffers from its legacy of being a not-quite-wild animal on the margins of society.
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Philadelphia hospital program adds psychologists to bridge mental health services for trauma survivors
A new psychology team at the Penn Trauma Violence Recovery Program has provided about 46 survivors with short- and long- term therapy, featuring remarks from Elinore Kaufman and Lily Brown of the Perelman School of Medicine.
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